Cell migration: implications for repair and regeneration in joint disease
Connective tissues within the synovial joints are characterized by their dense extracellular
matrix and sparse cellularity. With injury or disease, however, tissues commonly experience …
matrix and sparse cellularity. With injury or disease, however, tissues commonly experience …
A review of strategies for development of tissue engineered meniscal implants
GJ Klarmann, J Gaston, VB Ho - Biomaterials and Biosystems, 2021 - Elsevier
The meniscus is a key stabilizing tissue of the knee that facilitates proper tracking and
movement of the knee joint and absorbs stresses related to physical activity. This review …
movement of the knee joint and absorbs stresses related to physical activity. This review …
A biofabrication method to align cells within bioprinted photocrosslinkable and cell-degradable hydrogel constructs via embedded fibers
The extracellular matrix (ECM) is composed of biochemical and biophysical cues that control
cell behaviors and bulk mechanical properties. For example, anisotropy of the ECM and cell …
cell behaviors and bulk mechanical properties. For example, anisotropy of the ECM and cell …
Evaluation of biomimetic hyaluronic-based hydrogels with enhanced endogenous cell recruitment and cartilage matrix formation
Biomaterials play a pivotal role in cell-free cartilage repair approaches, where cells must
migrate through the scaffold, fill the defect, and then proliferate and differentiate facilitating …
migrate through the scaffold, fill the defect, and then proliferate and differentiate facilitating …
Actomyosin contractility-dependent matrix stretch and recoil induces rapid cell migration
Cells select from a diverse repertoire of migration strategies. Recent developments in
tunable biomaterials have helped identify how extracellular matrix properties influence …
tunable biomaterials have helped identify how extracellular matrix properties influence …
Recellularization and integration of dense extracellular matrix by percolation of tissue microparticles
JE Barthold, BM St. Martin, SL Sridhar… - Advanced functional …, 2021 - Wiley Online Library
Cells embedded in the extracellular matrix of tissues play a critical role in maintaining
homeostasis while promoting integration and regeneration following damage or disease …
homeostasis while promoting integration and regeneration following damage or disease …
Influence of fiber stiffness on meniscal cell migration into dense fibrous networks
Fibrous scaffolds fabricated via electrospinning are being explored to repair injuries within
dense connective tissues. However, there is still much to be understood regarding the …
dense connective tissues. However, there is still much to be understood regarding the …
Nuclear softening expedites interstitial cell migration in fibrous networks and dense connective tissues
Dense matrices impede interstitial cell migration and subsequent repair. We hypothesized
that nuclear stiffness is a limiting factor in migration and posited that repair could be …
that nuclear stiffness is a limiting factor in migration and posited that repair could be …
3D-Reactive printing of engineered alginate inks
Alginate is a common component of bioinks due to its well-described ionic crosslinking
mechanism and tunable viscoelastic properties. Extrusion-based 3D-printing of alginate inks …
mechanism and tunable viscoelastic properties. Extrusion-based 3D-printing of alginate inks …
[HTML][HTML] A hydrogel spinal dural patch with potential anti-inflammatory, pain relieving and antibacterial effects
J Li, J Tian, C Li, L Chen, Y Zhao - Bioactive materials, 2022 - Elsevier
CSFL caused by spinal dural defect is a common complication of spinal surgery, which need
repair such as suture or sealants. However, low intracranial pressure symptoms, wound …
repair such as suture or sealants. However, low intracranial pressure symptoms, wound …