Completing 'Summary of findings' tables and grading the certainty of the evidence

HJ Schünemann, JPT Higgins, GE Vist… - … systematic reviews of …, 2019 - Wiley Online Library
Planning for the 'Summary of findings' table starts early in the systematic review, with the
selection of the outcomes to be included in: the review; and the 'Summary of findings' table …

Nonalcoholic fatty liver disease and risk of incident type 2 diabetes: a meta-analysis

A Mantovani, CD Byrne, E Bonora, G Targher - Diabetes care, 2018 - Am Diabetes Assoc
OBJECTIVE Several studies have explored the impact of nonalcoholic fatty liver disease
(NAFLD) on risk of incident type 2 diabetes. However, the extent to which NAFLD may confer …

Computerised clinical decision support systems and absolute improvements in care: meta-analysis of controlled clinical trials

JL Kwan, L Lo, J Ferguson, H Goldberg… - Bmj, 2020 - bmj.com
Objective To report the improvements achieved with clinical decision support systems and
examine the heterogeneity from pooling effects across diverse clinical settings and …

The effects of psychotherapies for depression on response, remission, reliable change, and deterioration: A meta‐analysis

P Cuijpers, E Karyotaki, M Ciharova… - Acta Psychiatrica …, 2021 - Wiley Online Library
Objective Meta‐analyses of psychotherapies usually report effects sizes, while clinicians
and patients need to know the proportion of patients who benefit from therapy. We …

Non-alcoholic fatty liver disease and risk of incident cardiovascular disease: a meta-analysis

G Targher, CD Byrne, A Lonardo, G Zoppini… - Journal of …, 2016 - Elsevier
Background & Aims There have been many studies of the effects of non-alcoholic fatty liver
disease (NAFLD) and the risk of cardiovascular disease (CVD), but these have produced …

Personalized evidence based medicine: predictive approaches to heterogeneous treatment effects

DM Kent, E Steyerberg, D Van Klaveren - Bmj, 2018 - bmj.com
The use of evidence from clinical trials to support decisions for individual patients is a form of
“reference class forecasting”: implicit predictions for an individual are made on the basis of …

Initial treatment choices to achieve sustained response in major depression: a systematic review and network meta‐analysis

TA Furukawa, K Shinohara, E Sahker… - World …, 2021 - Wiley Online Library
Major depression is often a relapsing disorder. It is therefore important to start its treatment
with therapies that maximize the chance of not only getting the patients well but also keeping …

GRADE guidelines: 7. Rating the quality of evidence—inconsistency

GH Guyatt, AD Oxman, R Kunz, J Woodcock… - Journal of clinical …, 2011 - Elsevier
This article deals with inconsistency of relative (rather than absolute) treatment effects in
binary/dichotomous outcomes. A body of evidence is not rated up in quality if studies yield …

GRADE guidelines: 2. Framing the question and deciding on important outcomes

GH Guyatt, AD Oxman, R Kunz, D Atkins… - Journal of clinical …, 2011 - Elsevier
GRADE requires a clear specification of the relevant setting, population, intervention, and
comparator. It also requires specification of all important outcomes—whether evidence from …

GRADE guidelines: 12. Preparing summary of findings tables—binary outcomes

GH Guyatt, AD Oxman, N Santesso, M Helfand… - Journal of clinical …, 2013 - Elsevier
Summary of Findings (SoF) tables present, for each of the seven (or fewer) most important
outcomes, the following: the number of studies and number of participants; the confidence in …