A review on locomotor training after spinal cord injury: reorganization of spinal neuronal circuits and recovery of motor function

AC Smith, M Knikou - Neural plasticity, 2016 - Wiley Online Library
Locomotor training is a classic rehabilitation approach utilized with the aim of improving
sensorimotor function and walking ability in people with spinal cord injury (SCI). Recent …

Neural control of locomotion and training-induced plasticity after spinal and cerebral lesions

M Knikou - Clinical Neurophysiology, 2010 - Elsevier
Standing and walking require a plethora of sensorimotor interactions that occur throughout
the nervous system. Sensory afferent feedback plays a crucial role in the rhythmical muscle …

Repeated transspinal stimulation decreases soleus H-reflex excitability and restores spinal inhibition in human spinal cord injury

M Knikou, LM Murray - PLoS One, 2019 - journals.plos.org
Transcutaneous spinal cord or transspinal stimulation over the thoracolumbar enlargement,
the spinal location of motoneurons innervating leg muscles, modulates neural circuits …

Direct evidence for decreased presynaptic inhibition evoked by PBSt group I muscle afferents after chronic SCI and recovery with step‐training in rats

G Caron, JN Bilchak, MP Côté - The Journal of physiology, 2020 - Wiley Online Library
Key points Presynaptic inhibition is modulated by supraspinal centres and primary afferents
in order to filter sensory information, adjust spinal reflex excitability, and ensure smooth …

Differential modulation of spinal and corticospinal excitability during drop jumps

W Taube, C Leukel, M Schubert… - Journal of …, 2008 - journals.physiology.org
Previously it was shown that spinal excitability during hopping and drop jumping is high in
the initial phase of ground contact when the muscle is stretched but decreases toward …

Restoring walking after spinal cord injury: operant conditioning of spinal reflexes can help

AK Thompson, JR Wolpaw - The Neuroscientist, 2015 - journals.sagepub.com
People with incomplete spinal cord injury (SCI) frequently suffer motor disabilities due to
spasticity and poor muscle control, even after conventional therapy. Abnormal spinal reflex …

Integration of sensory, spinal, and volitional descending inputs in regulation of human locomotion

Y Gerasimenko, P Gad, D Sayenko… - Journal of …, 2016 - journals.physiology.org
We reported previously that both transcutaneous electrical spinal cord stimulation and direct
pressure stimulation of the plantar surfaces of the feet can elicit rhythmic involuntary step …

Afferent input and sensory function after human spinal cord injury

RA Ozdemir, MA Perez - Journal of neurophysiology, 2018 - journals.physiology.org
Spinal cord injury (SCI) often disrupts the integrity of afferent (sensory) axons projecting
through the spinal cord dorsal columns to the brain. Examinations of ascending sensory …

Modulation of soleus stretch reflexes during walking in people with chronic incomplete spinal cord injury

AK Thompson, N Mrachacz-Kersting, T Sinkjær… - Experimental brain …, 2019 - Springer
In people with spasticity due to chronic incomplete spinal cord injury (SCI), it has been
presumed that the abnormal stretch reflex activity impairs gait. However, locomotor stretch …

Afferent regulation of leg motor cortex excitability after incomplete spinal cord injury

FD Roy, JF Yang, MA Gorassini - Journal of …, 2010 - journals.physiology.org
An incomplete spinal cord injury (SCI) impairs neural conduction along spared ascending
sensory pathways to disrupt the control of residual motor movements. To characterize how …