Oxidative stress is the result of the imbalance between reactive oxygen species (ROS)
formation and enzymatic and nonenzymatic antioxidants. Biomarkers of oxidative stress are …

COVID-19 is announced as a global pandemic in 2020. Its mortality and morbidity rate are
rapidly increasing, with limited medications. The emergent outbreak of COVID-19 prompted …

The drug efflux pump P‐glycoprotein (P‐gp) plays an important role in the function of the
blood–brain barrier by selectively extruding certain endogenous and exogenous molecules …

We introduce the microfluidic organoids for drug screening (MODS) platform, a digital
microfluidic system that is capable of generating arrays of individually addressable, free …

Adverse drug reactions (ADRs) are one of the major causes of morbidity and mortality
worldwide. It is well-known that individual genetic make-up is one of the causative factors of …

Abstract Coronavirus Disease 2019 (COVID-19) has been a global health crisis since it was
first identified in December 2019. In addition to fever, cough, headache, and shortness of …

At the end of 2019, the entire world has witnessed the birth of a new member of coronavirus
family in Wuhan, China. Ever since, the Severe Acute Respiratory Syndrome Coronavirus 2 …

Background. Tenofovir (TFV) causes kidney tubular dysfunction (KTD) in some patients, but
the mechanism is poorly understood. Genetic variants in TFV transporters are implicated; we …

Review evaluates the possible physiological roles of MDR-related ABC transporters on
immune effector cells based on reports on their expression patterns and immune-related …

BACKGROUND: Multiple chemical sensitivity (MCS) is a poorly clinically and biologically
defined environment-associated syndrome. Although dysfunctions of phase I/phase II …