This paper is the forty-fifth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Antibiotic resistance has become an increasing challenge in the treatment of various
infectious diseases, especially those associated with biofilm formation on biotic and abiotic …

The most frequently reported use of medical marijuana is for pain relief. However, its
psychoactive component Δ9-tetrahydrocannabinol (THC) causes significant side effects …

The endocannabinoid system (ECS) dynamically regulates many aspects of mammalian
physiology. ECS has gained substantial interest since growing evidence suggests that it …

Chronic pain is a persistent, complex condition that contributes to impaired mood, anxiety
and emotional problems. Osteoarthritis (OA) is one of the major causes of chronic pain in …

As cannabinoid CB2 receptors (CB2R) possess various pharmacological effects—including
anti-epilepsy, analgesia, anti-inflammation, anti-fibrosis, and regulation of bone metabolism …

Osteoarthritis (OA) remains a challenging condition due to limited drug bioavailability within
the avascular and dense cartilage matrix. This study introduces a pH/redox-responsive …

Collaborative manual image analysis by multiple experts in different locations is an essential
workflow in biomedical science. However, sharing the images and writing down results by …

The investigation of therapeutic agents for Acanthamoeba keratitis (AK) is necessary as
nonspecific, toxic, and long-lasting treatments are currently found. In this study, ß …

Although rare, amoebic keratitis (AK) is a disease caused by Acanthamoeba spp. that can
lead to blindness. The drugs currently available for its treatment are very toxic, which has …