In the commonly accepted paradigm for control of the mammalian cell cycle, sequential
cyclin-dependent kinase (CDK) and cyclin activities drive the orderly transition from G1 to S …

Extracellular vesicles (EVs) play a key role in many physiological and pathophysiological
processes and hold great potential for therapeutic and diagnostic use. Despite significant …

Extracellular vesicles (EVs) have been established to play important roles in cell-cell
communication and shown promise as therapeutic agents. However, we still lack a basic …

How to generate a brain of correct size and with appropriate cell-type diversity during
development is a major question in Neuroscience. In the developing neocortex, radial glial …

Osseointegration of implants is a complex physiological process that requires temporal and
spatial regulation of immune responses, angiogenesis, and osteogenesis. To achieve …

Extracellular vesicles (EVs) are nanosized cell‐derived vesicles produced by all cells, which
provide a route of intercellular communication by transmitting biological cargo. While EVs …

Background Radiotherapy is a conventional and effective local treatment for breast cancer.
However, residual or recurrent tumors appears frequently because of radioresistance. Novel …

Genetic mutations that cause adult-onset neurodegenerative diseases are often expressed
during embryonic stages, but it is unclear whether they alter neurodevelopment and how this …

Non-excitable cells express sodium voltage-gated channel alpha subunit 1 gene and
protein (known as SCN1A and NaV1. 1, respectively); however, the functions of NaV1. 1 are …

Abstract Development and maintenance of diverse organ systems require context‐specific
regulation of stem cell behaviour. We hypothesize that this is achieved via reciprocal …