Oxidative stress and mitochondrial damage are the main mechanisms of ischemia-
reperfusion injury in ischemic stroke. Herein, cerium oxide nanoparticles with powerful free …

Stroke is one of the leading causes of death and disability globally. A significant proportion
of stroke survivors are left with long term neurological deficits that have a detrimental effect …

Cardiovascular diseases (CVD) are one of the leading causes of morbidity and mortality
worldwide. mtDNA (mitochondrial DNA) mutations are known to participate in the …

Intracerebral haemorrhage (ICH) accounts for half of the disability-adjusted life years lost
due to stroke worldwide. Care pathways for acute stroke result in the rapid identification of …

Abstract Background Cerebrovascular Diseases (CVD) constitute more than 50% of
neurological diseases requiring hospital treatment. Stroke is a type of disease that causes …

Restoring perfusion to ischemic tissue is the primary goal of acute ischemic stroke care, yet
only a small portion of patients receive reperfusion treatment. Since blood pressure (BP) is …

Although estrogen is predominantly related to the maintenance of reproductive functioning
in females, it mediates various physiological effects in nearly all tissues, especially the …

Neuroinflammation is a key factor that contributes to the secondary damage after cerebral
ischemia/reperfusion (CI/R) injury. Chemokine receptor type 5 (CCR5) has shown its pro …

Herein, we report the synthesis, antioxidant and biological evaluation of 32 monosubstituted
α-arylnitrones derived from α-phenyl-tert-butyl nitrone (PBN) in the search for …

Cerebral ischemic injury, one of the leading causes of morbidity and mortality worldwide,
triggers various central nervous system (CNS) diseases, including acute ischemic stroke …