Antimicrobial resistance monitoring of water environments: a framework for standardized methods and quality control

K Liguori, I Keenum, BC Davis, J Calarco… - … science & technology, 2022 - ACS Publications
Antimicrobial resistance (AMR) is a grand societal challenge with important dimensions in
the water environment that contribute to its evolution and spread. Environmental monitoring …

Metagenomics-enabled microbial surveillance

KKK Ko, KR Chng, N Nagarajan - Nature Microbiology, 2022 - nature.com
Lessons learnt from the COVID-19 pandemic include increased awareness of the potential
for zoonoses and emerging infectious diseases that can adversely affect human health …

ResFinder–an open online resource for identification of antimicrobial resistance genes in next-generation sequencing data and prediction of phenotypes from …

AF Florensa, RS Kaas, PTLC Clausen… - Microbial …, 2022 - microbiologyresearch.org
Antimicrobial resistance (AMR) is one of the most important health threats globally. The
ability to accurately identify resistant bacterial isolates and the individual antimicrobial …

AMRFinderPlus and the Reference Gene Catalog facilitate examination of the genomic links among antimicrobial resistance, stress response, and virulence

M Feldgarden, V Brover, N Gonzalez-Escalona… - Scientific reports, 2021 - nature.com
Antimicrobial resistance (AMR) is a significant public health threat. With the rise of affordable
whole genome sequencing, in silico approaches to assessing AMR gene content can be …

Genomic surveillance for antimicrobial resistance—a One Health perspective

SP Djordjevic, VM Jarocki, T Seemann… - Nature Reviews …, 2024 - nature.com
Antimicrobial resistance (AMR)—the ability of microorganisms to adapt and survive under
diverse chemical selection pressures—is influenced by complex interactions between …

The PATRIC Bioinformatics Resource Center: expanding data and analysis capabilities

JJ Davis, AR Wattam, RK Aziz, T Brettin… - Nucleic acids …, 2020 - academic.oup.com
Abstract The PathoSystems Resource Integration Center (PATRIC) is the bacterial
Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious …

CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database

BP Alcock, AR Raphenya, TTY Lau… - Nucleic acids …, 2020 - academic.oup.com
Abstract The Comprehensive Antibiotic Resistance Database (CARD; https://card. mcmaster.
ca) is a curated resource providing reference DNA and protein sequences, detection models …

Validating the AMRFinder tool and resistance gene database by using antimicrobial resistance genotype-phenotype correlations in a collection of isolates

M Feldgarden, V Brover, DH Haft… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Antimicrobial resistance (AMR) is a major public health problem that requires publicly
available tools for rapid analysis. To identify AMR genes in whole-genome sequences, the …

Antimicrobial resistance in bacteria: mechanisms, evolution, and persistence

E Christaki, M Marcou, A Tofarides - Journal of molecular evolution, 2020 - Springer
In recent years, we have seen antimicrobial resistance rapidly emerge at a global scale and
spread from one country to the other faster than previously thought. Superbugs and …

Clinical metagenomic sequencing for diagnosis of meningitis and encephalitis

MR Wilson, HA Sample, KC Zorn… - … England Journal of …, 2019 - Mass Medical Soc
Background Metagenomic next-generation sequencing (NGS) of cerebrospinal fluid (CSF)
has the potential to identify a broad range of pathogens in a single test. Methods In a 1-year …