Acetalated dextran (Ac-DEX) is a pH-responsive dextran derivative polymer. Prepared by a
simple acetalation reaction, Ac-DEX has tunable acid-triggered release profile. Despite its …

Polysaccharide biomaterials with carbohydrate backbones are currently the subject of
material science and engineering research for anticancer applications. Polysaccharides …

Dextran has emerged as a promising biopolymer carrier for controlled release formulations
of pesticides. In this study, pH-sensitive acetalated dextran microparticles (Pyr@ Ac-Dex) are …

Significant advancements have been made in the domain of targeted anticancer therapy for
the management of malignancies in recent times. VEGFR-2 is characterised by its pivotal …

Urologic cancers accounted for more than two million new cases and around 0.8 million
deaths in 2020. Although surgery, chemotherapy, and radiotherapy, as well as castration for …

Background Nanoparticles play a crucial role in nanodiagnostics, radiation therapy of
cancer, and they are now widely used to effectively deliver drugs to specific sites, targeting …

(1) Background and Aim: All-trans retinoic acid (ATRA) induces differentiation and inhibits
growth of many cancer cells. However, resistance develops rapidly prompting the urgent …

Microbes secrete high molecular-weight polysaccharides of diverse structures into the
surrounding environment termed exopolysaccharides (EPSs). EPSs serve multifarious roles …

Artemisinin and its derivatives have been commonly used to treat malaria. However, the
emergence of resistance against artemisinin derivatives has posed a critical challenge in …

The long-lasting wounding of lung tissue that results in pulmonary fibrosis is a long-term,
gradual lung condition that eventually impairs breathing and causes respiratory failure. For …