Throughout the entire process of cancer aetiology, progression and metastasis, the
microenvironment of the local host tissue can be an active participant. Invasion occurs within …

The marine environment has proven to be a very rich source of extremely potent compounds
that have demonstrated significant activities in antitumor, antiinflammatory, analgesia …

Terpenoids represent a diverse class of molecules that provide a wealth of opportunities to
address many human health and societal issues. The expansive array of structures and …

Covering: 31st December 2004Natural product and natural product-derived compounds that
are being evaluated in clinical trials or in registration (current 31 December 2004) have …

Covering: up to 2012 Steroids, a widespread class of natural organic compounds occurring
in animals, plants and fungi, have shown great therapeutic value for a broad array of …

Amyloids result from the aggregation of a set of diverse proteins, due to either specific
mutations or promoting intra-or extra-cellular conditions. Structurally, they are rich in …

Diabetic macular edema (DME) is a critical complication of diabetic retinopathy, a condition
that arises from the breakdown of the blood–retinal barrier and the consequent increase in …

Covering: 1993 to 2021 (mainly 2017–2021) Alzheimer's and Parkinson's diseases are
neurodegenerative conditions affecting over 50 million people worldwide. Since these …

The aggregation of α-synuclein, an intrinsically disordered protein that is highly abundant in
neurons, is closely associated with the onset and progression of Parkinson's disease. We …

Over 60% of the current anticancer drugs have their origin in one way or another from
natural sources. Nature continues to be the most prolific source of biologically active and …