Faecalibacterium: a bacterial genus with promising human health applications

R Martín, D Rios-Covian, E Huillet… - FEMS Microbiology …, 2023 - academic.oup.com
In humans, many diseases are associated with alterations in gut microbiota, namely
increases or decreases in the abundance of specific bacterial groups. One example is the …

Changes of colonic bacterial composition in Parkinson's disease and other neurodegenerative diseases

S Gerhardt, MH Mohajeri - Nutrients, 2018 - mdpi.com
In recent years evidence has emerged that neurodegenerative diseases (NDs) are strongly
associated with the microbiome composition in the gut. Parkinson's disease (PD) is the most …

Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer

L Derosa, B Routy, AM Thomas, V Iebba, G Zalcman… - Nature medicine, 2022 - nature.com
Aside from PD-L1 expression, biomarkers of response to immune checkpoint inhibitors (ICIs)
in non-small-cell lung cancer (NSCLC) are needed. In a previous retrospective analysis, we …

Alterations in the Abundance and Co-occurrence of Akkermansia muciniphila and Faecalibacterium prausnitzii in the Colonic Mucosa of Inflammatory Bowel …

M Lopez-Siles, N Enrich-Capó, X Aldeguer… - Frontiers in cellular …, 2018 - frontiersin.org
Akkermansia muciniphila and Faecalibacterium prausnitzii, cohabitants in the intestinal
mucosa, are considered members of a healthy microbiota and reduction of both species …

Faecalibacterium prausnitzii‐derived microbial anti‐inflammatory molecule regulates intestinal integrity in diabetes mellitus mice via modulating tight junction protein …

J Xu, R Liang, W Zhang, K Tian, J Li, X Chen… - Journal of …, 2020 - Wiley Online Library
Background Impaired intestinal barrier structure and function have been validated as an
important pathogenic process in type 2 diabetes mellitus (T2DM). Gut dysbiosis is thought to …

[HTML][HTML] Newly explored Faecalibacterium diversity is connected to age, lifestyle, geography, and disease

F De Filippis, E Pasolli, D Ercolini - Current Biology, 2020 - cell.com
Faecalibacterium is prevalent in the human gut and a promising microbe for the
development of next-generation probiotics (NGPs) or biotherapeutics. Analyzing reference …

Species-targeted sorting and cultivation of commensal bacteria from the gut microbiome using flow cytometry under anaerobic conditions

S Bellais, M Nehlich, M Ania, A Duquenoy, W Mazier… - Microbiome, 2022 - Springer
Background There is a growing interest in using gut commensal bacteria as “next
generation” probiotics. However, this approach is still hampered by the fact that there are …

[HTML][HTML] Gut microbiota changes and its potential relations with thyroid carcinoma

X Yu, W Jiang, RO Kosik, Y Song, Q Luo, T Qiao… - Journal of advanced …, 2022 - Elsevier
Introduction Emerging evidence suggests that the essence of life is the ecological balance of
the neural, endocrine, metabolic, microbial, and immune systems. Gut microbiota have been …

Phages infecting Faecalibacterium prausnitzii belong to novel viral genera that help to decipher intestinal viromes

JK Cornuault, MA Petit, M Mariadassou, L Benevides… - Microbiome, 2018 - Springer
Background Viral metagenomic studies have suggested a role for bacteriophages in
intestinal dysbiosis associated with several human diseases. However, interpretation of viral …

Genome-based, phenotypic and chemotaxonomic classification of Faecalibacterium strains: proposal of three novel species Faecalibacterium duncaniae sp. nov …

M Sakamoto, N Sakurai, H Tanno… - … of Systematic and …, 2022 - microbiologyresearch.org
Faecalibacterium prausnitzii is one of the most important butyrate-producing bacteria in the
human gut. Previous studies have suggested the presence of several phylogenetic groups …