From the first experiments of the atomic force microscopy (AFM) with biological samples, the
range of its potential applications grows extensively. One of them is the use of AFM to …

dimethylhydrazine (DMH) is a member in the class of hydrazines, strong DNA alkylating
agent, naturally present in cycads. DMH is widely used as a carcinogen to induce colon …

Background Chronic high-fat diet (HFD) consumption caused not only obese-insulin
resistance, but also cognitive decline and microglial hyperactivity. Modified gut microbiota by …

The stiffness of cancer cells and its changes during metastasis are very important for
understanding the pathophysiology of cancer cells and the mechanisms of metastasis of …

The delivery of curcumin has been explored in the form of liposomal nanoparticles to treat
various cancer cells. Since curcumin is water insoluble and an effective delivery route is …

Epithelial cells maintain an essential barrier despite continuously undergoing mitosis and
apoptosis. Biological and biophysical mechanisms have evolved to remove dying cells while …

The excessive production of endogenous hydrogen sulfide (H2S) in cancer cells leads to
enhanced tumor growth and metastasis. On the other hand, decreased endogenous H2S …

Since the crucial role of the microenvironment has been highlighted, many studies have
been focused on the role of biomechanics in cancer cell growth and the invasion of the …

Regulated cell death (RCD) has a fundamental role in development, pathology, and tissue
homeostasis. In order to understand the RCD mechanisms, it is essential to follow these …

The roughness of cell membrane is a very interesting indicator of cell's health state. Atomic
Force Microscopy allows us to investigate the roughness of cell membrane in great detail …