Toxicology and pharmacology of synthetic organoselenium compounds: An update

CW Nogueira, NV Barbosa, JBT Rocha - Archives of Toxicology, 2021 - Springer
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …

Organoselenium and organotellurium compounds: toxicology and pharmacology

CW Nogueira, G Zeni, JBT Rocha - Chemical reviews, 2004 - ACS Publications
Organoselenium compounds have found such wide utility because of their effects on an
extraordinary number of very different reactions, including many carbon-carbon bond …

Toxicology and pharmacology of selenium: emphasis on synthetic organoselenium compounds

CW Nogueira, JBT Rocha - Archives of Toxicology, 2011 - Springer
The advance in the area of synthesis and reactivity of organoselenium, as well as the
discovery that selenium was the cause of severe intoxication episodes of livestock in the …

Antioxidant-prooxidant properties of a new organoselenium compound library

D Plano, Y Baquedano, E Ibáñez, I Jiménez, JA Palop… - Molecules, 2010 - mdpi.com
The present study describes the biological evaluation of a library of 59 organo-selenium
compounds as superoxide (O2─) generators and cytotoxic agents in human prostate cancer …

Cytotoxicity of 4-substituted quinoline derivatives: anticancer and antileishmanial potential

CA Costa, RM Lopes, LS Ferraz, GNN Esteves… - Bioorganic & Medicinal …, 2020 - Elsevier
Chemical modifications of quinoline moiety have been recognized as a useful strategy to
development of new drugs. Here, the cytotoxicity of a set of twenty-four 4-substituted …

[HTML][HTML] Nobiletin exhibits neuroprotective effects against mitochondrial complex I inhibition via regulating apoptotic signaling

K Amarsanaa, HJ Kim, EA Ko, J Jo… - Experimental …, 2021 - ncbi.nlm.nih.gov
Nobiletin, a polymethoxylated flavonoid found in citrus, has been studied because of its
modulatory functions in cellular signaling cascades, and effects to prevent mitochondrial …

Effect of garlic-derived organosulfur compounds on mitochondrial function and integrity in isolated mouse liver mitochondria

AA Caro, LW Adlong, SJ Crocker, MW Gardner… - Toxicology letters, 2012 - Elsevier
The objectives of this work were to evaluate the direct effects of diallysulfide (DAS) and
diallyldisulfide (DADS), two major organosulfur compounds of garlic oil, on mitochondrial …

Acute brain damage induced by acetaminophen in mice: effect of diphenyl diselenide on oxidative stress and mitochondrial dysfunction

MH da Silva, EJF da Rosa, NR de Carvalho… - Neurotoxicity …, 2012 - Springer
Organoselenium compounds exhibit antioxidant activity, as well as a variety of biological
activities, with potential pharmacological and therapeutic applications. The aim of this study …

Organodiselenides: Organic catalysis and drug design learning from glutathione peroxidase

MD Tiezza, G Ribaudo, L Orian - Current Organic Chemistry, 2019 - ingentaconnect.com
Organodiselenides are an important class of compounds characterized by the presence of
two adjacent covalently bonded selenium nuclei. Among them, diaryldiselenides and their …

African eggplant (Solanum anguivi Lam.) fruit with bioactive polyphenolic compounds exerts in vitro antioxidant properties and inhibits Ca2+-induced mitochondrial …

OO Elekofehinti, JP Kamdem, AA Bolingon… - Asian Pacific journal of …, 2013 - Elsevier
Objective To evaluate the antioxidant and radical scavenging activities of Solanum anguivi
fruit (SAG) and its possible effect on mitochondrial permeability transition pore as well as …