Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually, including 875 million children in developing …

Piplartine (piperlongumine, 5, 6-dihydro-1-[(2E)-1-oxo-3-(3, 4, 5-trimethoxyphenyl)-2-
propenyl]-2 (1H)-pyridinone) is a biologically active alkaloid/amide from peppers, as from …

Background Schistosomiasis is a major endemic disease that affects hundreds of millions
worldwide. Since the treatment and control of this parasitic disease rely on a single drug …

Chagas disease, leishmaniasis and schistosomiasis are neglected diseases (NDs) and are
a considerable global challenge. Despite the huge number of people infected, NDs do not …

An overview is presented of the well-established role of alkaloids in drug discovery, the
application of more sustainable chemicals, and biological approaches, and the …

Infectious diseases caused by parasites are a major threat for the entire mankind, especially
in the tropics. More than 1 billion people world-wide are directly exposed to tropical …

In recent years, natural product groups have been gaining prominence as possible sources
of new drugs for schistosomiasis. This review attempts to update the antischistosomal …

Schistosomiasis is a neglected parasitic tropical disease that claims around 200,000 human
lives every year. Praziquantel (PZQ), the only drug recommended by the World Health …

Schistosomiasis is one of the most important parasitic infections in terms of its negative
effects on public health and economics. Since praziquantel is currently the only drug …

Ethnopharmacological relevance There are ethnopharmacological reports supporting the
use of neem (Azadirachta indica A. Juss) leaf against bacterial and worm infections …