Hypertension, thrombosis, kidney failure, and diabetes: is COVID-19 an endothelial disease? A comprehensive evaluation of clinical and basic evidence

C Sardu, J Gambardella, MB Morelli, X Wang… - Journal of clinical …, 2020 - mdpi.com
The symptoms most commonly reported by patients affected by coronavirus disease (COVID-
19) include cough, fever, and shortness of breath. However, other major events usually …

[HTML][HTML] Diabetes, infection risk and COVID-19

S Erener - Molecular metabolism, 2020 - Elsevier
Background Individuals with diabetes are at a greater risk of hospitalization and mortality
resulting from viral, bacterial, and fungal infections. The coronavirus disease-2019 (COVID …

Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies

R Kaur, M Kaur, J Singh - Cardiovascular diabetology, 2018 - Springer
The incidence and prevalence of diabetes mellitus is rapidly increasing worldwide at an
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …

Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases

MA Incalza, R D'Oria, A Natalicchio, S Perrini… - Vascular …, 2018 - Elsevier
Reactive oxygen species (ROS) are reactive intermediates of molecular oxygen that act as
important second messengers within the cells; however, an imbalance between generation …

Arginine and endothelial function

J Gambardella, W Khondkar, MB Morelli, X Wang… - Biomedicines, 2020 - mdpi.com
Arginine (L-arginine), is an amino acid involved in a number of biological processes,
including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide …

Endothelial dysfunction: is there a hyperglycemia-induced imbalance of NOX and NOS?

CA Meza, JD La Favor, DH Kim… - International journal of …, 2019 - mdpi.com
NADPH oxidases (NOX) are enzyme complexes that have received much attention as key
molecules in the development of vascular dysfunction. NOX have the primary function of …

High-intensity interval training: a review of its impact on glucose control and cardiometabolic health

S Cassidy, C Thoma, D Houghton, MI Trenell - Diabetologia, 2017 - Springer
Exercise plays a central role in the management and treatment of common metabolic
diseases, but modern society presents many barriers to exercise. Over the past decade …

Nanoparticle-based therapeutic approach for diabetic wound healing

H Ezhilarasu, D Vishalli, ST Dheen, BH Bay… - Nanomaterials, 2020 - mdpi.com
Diabetes mellitus (DM) is a common endocrine disease characterized by a state of
hyperglycemia (higher level of glucose in the blood than usual). DM and its complications …

Angiogenesis and inflammation crosstalk in diabetic retinopathy

M Capitão, R Soares - Journal of cellular biochemistry, 2016 - Wiley Online Library
Diabetic retinopathy (DR) is one of the most prevalent microvascular complications of
diabetes and one of the most frequent causes of blindness in active age. Etiopathogenesis …

[HTML][HTML] Multimodal sensing and therapeutic systems for wound healing and management: A review

SH Lu, M Samandari, C Li, H Li, D Song… - Sensors and Actuators …, 2022 - Elsevier
Wounds especially chronic ones significantly affect the quality of patients' life and present a
severe financial burden for the healthcare industry. Timely and effective management of …