Epigenetic alterations in colorectal cancer: emerging biomarkers

Y Okugawa, WM Grady, A Goel - Gastroenterology, 2015 - Elsevier
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. One of the
fundamental processes driving the initiation and progression of CRC is the accumulation of …

A uniform system for the annotation of vertebrate microRNA genes and the evolution of the human microRNAome

B Fromm, T Billipp, LE Peck, M Johansen… - Annual review of …, 2015 - annualreviews.org
Although microRNAs (miRNAs) are among the most intensively studied molecules of the
past 20 years, determining what is and what is not a miRNA has not been straightforward …

[HTML][HTML] Cancer-associated fibroblasts release exosomal microRNAs that dictate an aggressive phenotype in breast cancer

E Donnarumma, D Fiore, M Nappa, G Roscigno… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Cancer-associated fibroblasts (CAFs) are the major components of the tumor
microenvironment. They may drive tumor progression, although the mechanisms involved …

[HTML][HTML] Curcumin inhibits cell proliferation and induces apoptosis of human non-small cell lung cancer cells through the upregulation of miR-192-5p and suppression …

H Jin, F Qiao, Y Wang, Y Xu… - Oncology …, 2015 - spandidos-publications.com
Curcumin is the main active ingredient extracted from the traditional Chinese medicine,
turmeric, which acts against non-small cell lung cancer cell (NSCLC), lowers blood …

Multi-omics approaches in colorectal cancer screening and diagnosis, recent updates and future perspectives

I Ullah, L Yang, FT Yin, Y Sun, XH Li, J Li, XJ Wang - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is one of the most prevalent cancers worldwide.
Due to the absence of specific early symptoms, most of CRC patients are often diagnosed at …

[HTML][HTML] The fundamental role of miR-10b in metastatic cancer

P Sheedy, Z Medarova - American journal of cancer research, 2018 - ncbi.nlm.nih.gov
Small, non-coding strands of RNA have been identified as a significant player in the
pathology of cancer. One of the first miRNAs to be shown as having aberrant expression in …

Circulating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitis

J Ward, C Kanchagar… - Proceedings of the …, 2014 - National Acad Sciences
We have identified, by quantitative real-time PCR, hundreds of miRNAs that are dramatically
elevated in the plasma or serum of acetaminophen (APAP) overdose patients. Most of these …

[HTML][HTML] Omics technologies for improved diagnosis and treatment of colorectal cancer: Technical advancement and major perspectives

N Dalal, R Jalandra, M Sharma, H Prakash… - Biomedicine & …, 2020 - Elsevier
Colorectal cancer (CRC) ranks third among the most commonly occurring cancers
worldwide, and it causes half a million deaths annually. Alongside mechanistic study for …

High mobility group box 1 in human cancer

BL Rapoport, HC Steel, AJ Theron, L Heyman, T Smit… - Cells, 2020 - mdpi.com
High mobility group box 1 (HMGB1) is an extremely versatile protein that is located
predominantly in the nucleus of quiescent eukaryotic cells, where it is critically involved in …

Hsa_circRNA_002144 promotes growth and metastasis of colorectal cancer through regulating miR-615-5p/LARP1/mTOR pathway

M Wu, C Kong, M Cai, W Huang, Y Chen… - …, 2021 - academic.oup.com
CircRNAs (circular RNAs), recently identified as a critical regulator in tumorigenesis,
participate in CRC (colorectal cancer) growth. However, the role of hsa_circRNA_002144 in …