While gap junctions support the exchange of a number of molecules between neighboring
cells, connexin hemichannels provide communication between the cytosol and the …

Cys-loop receptors are membrane-spanning neurotransmitter-gated ion channels that are
responsible for fast excitatory and inhibitory transmission in the peripheral and central …

From killers to curers: Peptides from cone snail venoms are potential therapeutic agents for
the treatment of neuropathic pain. Unfortunately, these peptides suffer from the …

Alkaloid‐containing plants are an intrinsic part of the regular Western diet. The present
paper summarizes the occurrence of alkaloids in the food chain, their mode of action and …

The 5-HT3 receptor is a neurotransmitter-gated ion channel. It is a member of the Cys-loop
family of receptors, which also includes nicotinic acetylcholine, glycine and GABAA …

Serotonin type 3 (5-HT3) receptors are pentameric ion channels belonging to the
superfamily of Cys-loop receptors. Receptor activation either leads to fast excitatory …

Gap junctions play an important role in brain physiology. They synchronize neuronal activity
and connect glial cells participating in the regulation of brain metabolism and homeostasis …

Alkaloids are a huge class of natural occurring organic molecules, which contain nitrogen
atom or atoms (amino or amido in some cases) in their structures. Alkaloids are extremely …

Epilepsy is the most common chronic neurological disease, affecting about 1% of the world's
population during their lifetime. Most people with epilepsy can attain a seizure-free life upon …

Nicotinic acetylcholine receptors (nAChRs) present as many different subtypes in the
nervous and immune systems, muscles and on the cells of other organs. In the immune …