mRNA-based therapeutics: powerful and versatile tools to combat diseases
S Qin, X Tang, Y Chen, K Chen, N Fan… - Signal transduction and …, 2022 - nature.com
The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …
range of incurable diseases. Recent rapid advances in biotechnology and molecular …
[HTML][HTML] mRNA vaccines—a new era in vaccinology
Abstract mRNA vaccines represent a promising alternative to conventional vaccine
approaches because of their high potency, capacity for rapid development and potential for …
approaches because of their high potency, capacity for rapid development and potential for …
[HTML][HTML] Immune reactions after modern lamellar (DALK, DSAEK, DMEK) versus conventional penetrating corneal transplantation
D Hos, M Matthaei, F Bock, K Maruyama… - Progress in retinal and …, 2019 - Elsevier
In the past decade, novel lamellar keratoplasty techniques such as Deep Anterior Lamellar
Keratoplasty (DALK) for anterior keratoplasty and Descemet stripping automated endothelial …
Keratoplasty (DALK) for anterior keratoplasty and Descemet stripping automated endothelial …
Clinical and immunological effects of mRNA vaccines in malignant diseases
In vitro-transcribed messenger RNA-based therapeutics represent a relatively novel and
highly efficient class of drugs. Several recently published studies emphasize the potential …
highly efficient class of drugs. Several recently published studies emphasize the potential …
mRNA vaccine: a potential therapeutic strategy
Y Wang, Z Zhang, J Luo, X Han, Y Wei, X Wei - Molecular cancer, 2021 - Springer
Abstract mRNA vaccines have tremendous potential to fight against cancer and viral
diseases due to superiorities in safety, efficacy and industrial production. In recent decades …
diseases due to superiorities in safety, efficacy and industrial production. In recent decades …
CD83: activation marker for antigen presenting cells and its therapeutic potential
CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane
bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated …
bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated …
Delivery strategies of cancer immunotherapy: recent advances and future perspectives
Z Zhao, L Zheng, W Chen, W Weng, J Song… - Journal of hematology & …, 2019 - Springer
Immunotherapy has become an emerging strategy for the treatment of cancer.
Immunotherapeutic drugs have been increasing for clinical treatment. Despite significant …
Immunotherapeutic drugs have been increasing for clinical treatment. Despite significant …
The CD83 molecule–an important immune checkpoint
L Grosche, I Knippertz, C König, D Royzman… - Frontiers in …, 2020 - frontiersin.org
The CD83 molecule has been identified to be expressed on numerous activated immune
cells, including B and T lymphocytes, monocytes, dendritic cells, microglia, and neutrophils …
cells, including B and T lymphocytes, monocytes, dendritic cells, microglia, and neutrophils …
The role of glycosphingolipids in immune cell functions
Glycosphingolipids (GSLs) exhibit a variety of functions in cellular differentiation and
interaction. Also, they are known to play a role as receptors in pathogen invasion. A less well …
interaction. Also, they are known to play a role as receptors in pathogen invasion. A less well …
Neo-antigen mRNA vaccines
A Esprit, W de Mey, R Bahadur Shahi, K Thielemans… - Vaccines, 2020 - mdpi.com
The interest in therapeutic cancer vaccines has caught enormous attention in recent years
due to several breakthroughs in cancer research, among which the finding that successful …
due to several breakthroughs in cancer research, among which the finding that successful …