Background The landscape of brain metastases radiotherapy is evolving, with a shift away
from whole-brain radiotherapy (WBRT) toward targeted stereotactic approaches aimed at …

All cancer patients experience distress from the diagnosis, the effects of the disease or the
treatment. Clinically significant distress decreases overall quality of life and the recognition …

Background and purpose The PRIDE trial (NOA-28; ARO-2022-12; NCT05871021) is
scheduled to start recruitment in October 2023. Its primary objective is to enhance median …

Background Patients affected by a high-grade glioma (HGG) have a poor prognosis with a
median survival of 12–16 months. Such poor prognosis affects the perception of the …

Background Gliomas make up approximately 26.5% of all primary CNS tumors and 80.7% of
malignant tumors. They are classified according to histology, location, and genetics. Grade …

Background The hippocampus is a critical organ for irradiation. Thus, we explored changes
in hippocampal volume according to the dose delivered and the location relative to the …

Radiotherapy remains currently a critical component for both primary and metastatic brain
tumors either alone or in combination with surgery, chemotherapy, and molecularly targeted …

Materials and Methods: A systematic review of published literature was performed on
PubMed and the Cochrane Library. Only prospective clinical trials reporting NCF outcome in …

This study aimed to explore the effects of radiochemotherapy on the neurocognitive function
of patients with high-grade gliomas (HGG). The mini-mental state examination (MMSE) …

Background In patients with recurrent glioblastoma, corticosteroids are frequently used to
mitigate intracranial pressure and to improve patient neurological functioning. To date, in …