Since its first splash 30 years ago, the use of the zebrafish model has been extended from a
tool for genetic dissection of early vertebrate development to the functional interrogation of …

Chronic lung disease determines the morbidity and mortality of cystic fibrosis (CF) patients.
The pulmonary immune response in CF is characterized by an early and non-resolving …

Macrophages and neutrophils play important roles during the innate immune response,
phagocytosing invading microbes and delivering antimicrobial compounds to the site of …

Mycobacterium abscessus is a rapidly growing Mycobacterium causing a wide spectrum of
clinical syndromes. It now is recognized as a pulmonary pathogen to which cystic fibrosis …

Cystic fibrosis (CF) remains the most common fatal hereditary lung disease. The discovery of
the cystic fibrosis transmembrane conductance regulator (CFTR) gene 25 years ago set the …

Cystic fibrosis (CF) is a hereditary disease due to mutations in the CFTR gene and causes
mortality in humans mainly due to respiratory infections caused by Pseudomonas …

The zebrafish holds much promise as a high-throughput drug screening model for immune-
related diseases, including inflammatory and infectious diseases and cancer. This is due to …

Pseudomonas aeruginosa is an opportunistic bacterium which induces some complications
in immunocompromised patients. Pseudomonas aeruginosa is a quorum-sensing using …

Cystic fibrosis (CF) is caused by defects in an anion channel, the cystic fibrosis
transmembrane conductance regulator (CFTR). Recently, a new airway epithelial cell type …

Neutrophils are highly motile phagocytic cells that play a critical role in the immune
response to infection. Zebrafish (Danio rerio) are increasingly used to study neutrophil …