Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders affecting
cortisol biosynthesis. Reduced activity of an enzyme required for cortisol production leads to …

Objectives: To address the prevention and treatment of acute and chronic pain in children,
including pain caused by needles, with recommended analgesic starting doses. Methods …

Background Long COVID in children and adolescents remains poorly understood due to a
lack of well-controlled studies with long-term follow-up. In particular, the impact of the family …

Although resilience and high quality of life are demonstrated by many individuals with
congenital heart disease, a range of significant psychological challenges exists across the …

Migraine, a common and disabling neurological disorder, is among the top reasons for
outpatient visits to general neurologists. In addition to pharmacotherapy, lifestyle …

OBJECTIVES The mental health of parents of children with medical complexity (CMC) is
poorly understood, yet it drives child and family health outcomes. For parents of CMC …

Chronic pain is a prevalent and persistent problem in middle childhood and adolescence.
The biopsychosocial model of pain, which accounts for the complex interplay of the …

Objective Juvenile fibromyalgia syndrome (FMS) is a chronic musculoskeletal pain disorder
in children and adolescents for which there are no evidence‐based treatments. The …

Pain that persists for longer than 3 months is common in childhood; 5% to 8% of youth report
severe and disabling chronic pain. 28 Pain can affect virtually all aspects of a child's life …

Chronic pain in childhood is an international public health problem. We conducted a
systematic review and meta-analysis to provide a summary of the published evidence of …