This review categorizes functionally validated actions of defined scorpion toxin (SCTX)
neuropeptides across ion channel subclasses, highlighting key trends in this rapidly …

Ion channels play a key role in our body to regulate homeostasis and conduct electrical
signals. With the help of advances in structural biology, as well as the discovery of numerous …

A novel peptide, Cm39, was identified in the venom of the scorpion Centruroides
margaritatus. Its primary structure was determined. It consists of 37 amino acid residues with …

Australian scorpion venoms have been poorly studied, probably because they do not pose
an evident threat to humans. In addition, the continent has other medically important …

Scorpion venom is an unmatched source of selective high-affinity ligands of potassium
channels. There is a high demand for such compounds to identify and manipulate the …

Scorpion venoms are natural sources of molecules that have, in addition to their toxic
function, potential therapeutic applications. In this source the neurotoxins can be found …

Hadogenes is a genus of large African scorpions with 18 described species. However, little
is known about the venom peptide composition of any species from Hadogenes so far. Here …

Aphids are severe agricultural pests that damage crops by feeding on phloem sap and
vectoring plant pathogens. Chemical insecticides provide an important aphid control …

Arthropod venoms are a rich mixture of biologically active compounds exerting different
physiological actions across diverse phyla and affecting multiple organ systems including …

Abstract Urotoxin (α-KTx 6), a peptide from venom of the Australian scorpion Urodacus
yaschenkoi, is the most potent inhibitor of Kv1. 2 described to date (IC 50= 160 pM). The …