Divergent Causes and Convergent Mechanisms of SUDEP.
GB Richerson - Annals of neurology, 2023 - search.ebscohost.com
There is considerable evidence that seizures can alter cardiac rate and rhythm, and
autonomic output.[15] SUDEP is clearly heterogeneous, and a subset not captured in …
autonomic output.[15] SUDEP is clearly heterogeneous, and a subset not captured in …
Ictal and Postictal Central Apnea in DEPDC5-Related Epilepsy
Objectives DEPDC5-related epilepsy carries an increased risk of sudden unexpected death
in epilepsy. We evaluated the occurrence and features of ictal central apnea (ICA) in …
in epilepsy. We evaluated the occurrence and features of ictal central apnea (ICA) in …
[HTML][HTML] Neuronal cell type specific roles for Nprl2 in neurodevelopmental disorder-relevant behaviors
B Dentel, L Angeles-Perez, AY Flores, K Lei… - Neurobiology of …, 2025 - Elsevier
Loss of function in the subunits of the GTPase-activating protein (GAP) activity toward Rags-
1 (GATOR1) complex, an amino-acid sensitive negative regulator of the mechanistic target …
1 (GATOR1) complex, an amino-acid sensitive negative regulator of the mechanistic target …
[HTML][HTML] Hsp90aa1/JUN/Ccl2 regulatory axis mediates migration and differentiation of NSPCs, promoting the onset and progression of early post-ischemic stroke …
Early-onset epilepsy following ischemic stroke is a severe neurological condition, the
pathogenesis of which remains incompletely understood. Recent studies suggest that …
pathogenesis of which remains incompletely understood. Recent studies suggest that …
Insights into DEPDC5-Related Epilepsy from 586 people: Variant Penetrance, Phenotypic Spectrum, and Treatment Outcomes
M Ochoa-Urrea, EA Butler, T Brunger, C Bosselmann… - medRxiv, 2024 - medrxiv.org
Variants in the GATOR1 complex gene DEPDC5 disrupt mTORC1 pathway regulation,
driving cortical malformations and focal epilepsy. DEPDC5 is the most common genetic …
driving cortical malformations and focal epilepsy. DEPDC5 is the most common genetic …
Dissecting The Tissue-Specific Contributions To Seizures, Cardiorespiratory Dysfunction, And Sudden Death In The Kv1. 1 Mouse Model Of Epilepsy Using …
K Paulhus - 2024 - scholar.smu.edu
Sudden unexpected death in epilepsy (SUDEP), the primary cause of mortality in epilepsy,
remains poorly understood. Studies suggest seizures may trigger dangerous signals …
remains poorly understood. Studies suggest seizures may trigger dangerous signals …