For around three decades, the fluoroquinolone (FQ) antibiotic ciprofloxacin has been used
to treat a range of diseases, including chronic otorrhea, endocarditis, lower respiratory tract …

Mycobacteria are the causative organisms for diseases such as tuberculosis (TB), leprosy,
Buruli ulcer, and pulmonary nontuberculous mycobacterial disease, to name the most …

Page 1 Catalogue of mutations in Mycobacterium tuberculosis complex and their
association with drug resistance Second edition Page 2 Page 3 Catalogue of mutations in …

2 Global tuberculosis report 2017. Geneva: World Health Organization; 2017 (WHO/HTM/TB/
2017.23; http://www. who. int/tb/publications/global_report/en/, accessed 1 November 2017) …

To characterize the genetic determinants of resistance to antituberculosis drugs, we
performed a genome-wide association study (GWAS) of 6,465 Mycobacterium tuberculosis …

Mycobacterium tuberculosis drug resistance (DR) challenges effective tuberculosis disease
control. Current molecular tests examine limited numbers of mutations, and although whole …

The incidence and prevalence of non-tuberculous mycobacterial (NTM) infections have
been increasing worldwide and lately led to an emerging public health problem. Among …

Drug-resistance testing, or antimicrobial susceptibility testing (AST), is mandatory for
Mycobacterium tuberculosis in cases of failure on standard therapy. We reviewed the …

Drug-resistant tuberculosis is a substantial health-care concern worldwide. Despite culture-
based methods being considered the gold standard for drug susceptibility testing, molecular …

The emergence of drug-resistant strains of Mycobacterium tuberculosis is a challenge to
global tuberculosis (TB) control. Although culture-based methods have been regarded as …