Although classically thought of as a motor circuit, the cerebellum is now understood to
contribute to a wide variety of cognitive functions through its dense interconnections with the …

Neuronal ensembles, defined as groups of neurons displaying recurring patterns of
coordinated activity, represent an intermediate functional level between individual neurons …

There is increasing evidence for a cerebellar contribution to cognitive processing, but the
specific input pathways conveying this information remain unclear. We probed the role of …

Throughout mammalian neocortex, layer 5 pyramidal (L5) cells project via the pons to a vast
number of cerebellar granule cells (GrCs), forming a fundamental pathway. Yet, it is …

Three decades of electrophysiological research on cerebellar cortical activity underlying
Pavlovian conditioning have expanded our understanding of motor learning in the brain …

Our motor outputs are constantly re-calibrated to adapt to systematic perturbations. This
motor adaptation is thought to depend on the ability to form a memory of a systematic …

In motor neuroscience, state changes are hypothesized to time-lock neural assemblies
coordinating complex movements, but evidence for this remains slender. We tested whether …

The coordination of movement across the body is a fundamental, yet poorly understood
aspect of motor control. Mutant mice with cerebellar circuit defects exhibit characteristic …

The cerebellum is well appreciated to impart speed, smoothness, and precision to skilled
movements such as reaching. How these functions are executed by the final output stage of …

Essential tremor (ET) is one of the most common movement disorders and the prototypical
disorder for abnormal rhythmic movements. However, the pathophysiology of tremor …