Tuberculosis: pathogenesis, current treatment regimens and new drug targets

SSR Alsayed, H Gunosewoyo - International journal of molecular …, 2023 - mdpi.com
Mycobacterium tuberculosis (M. tb), the causative agent of TB, is a recalcitrant pathogen that
is rife around the world, latently infecting approximately a quarter of the worldwide …

Recent advances in airborne pathogen detection using optical and electrochemical biosensors

R Sivakumar, NY Lee - Analytica chimica acta, 2022 - Elsevier
The world is currently facing an adverse condition due to the pandemic of airborne pathogen
SARS-CoV-2. Prevention is better than cure; thus, the rapid detection of airborne pathogens …

Volatolomics in healthcare and its advanced detection technology

W Hu, W Wu, Y Jian, H Haick, G Zhang, Y Qian… - Nano Research, 2022 - Springer
Various diseases increasingly challenge the health status and life quality of human beings.
Volatolome emitted from patients has been considered as a potential family of markers …

[HTML][HTML] Diagnosis and biomarkers for ocular tuberculosis: From the present into the future

Z Ludi, AA Sule, RP Samy, I Putera, B Schrijver… - Theranostics, 2023 - ncbi.nlm.nih.gov
Tuberculosis is an airborne disease caused by Mycobacterium tuberculosis (Mtb) and can
manifest both pulmonary and extrapulmonary disease, including ocular tuberculosis (OTB) …

Making cough count in tuberculosis care

AJ Zimmer, C Ugarte-Gil, R Pathri, P Dewan… - Communications …, 2022 - nature.com
Cough assessment is central to the clinical management of respiratory diseases, including
tuberculosis (TB), but strategies to objectively and unobtrusively measure cough are lacking …

Advances in diagnostics and drug discovery against resistant and latent tuberculosis infection

C Shleider Carnero Canales, J Marquez Cazorla… - Pharmaceutics, 2023 - mdpi.com
Latent tuberculosis infection (LTBI) represents a subclinical, asymptomatic mycobacterial
state affecting approximately 25% of the global population. The substantial prevalence of …

Cargoes of exosomes function as potential biomarkers for Mycobacterium tuberculosis infection

N Wang, Y Yao, Y Qian, D Qiu, H Cao, H Xiang… - Frontiers in …, 2023 - frontiersin.org
Exosomes as double-membrane vesicles contain various contents of lipids, proteins,
mRNAs and non-coding RNAs, and involve in multiple physiological processes, for instance …

[HTML][HTML] Pulmonary tuberculosis in intensive care setting, with a focus on the use of severity scores, a multinational collaborative systematic review

J Galvin, S Tiberi, O Akkerman, HAM Kerstjens… - Pulmonology, 2022 - Elsevier
Background and aim Tuberculosis (TB) is associated with a high mortality in the intensive
care unit (ICU), especially in subjects with Acute Respiratory Distress Syndrome (ARDS) …

Diagnostics of tuberculosis with single-walled carbon nanotube-based field-effect transistors

J Wang, W Shao, Z Liu, G Kesavan, Z Zeng… - ACS …, 2024 - ACS Publications
Tuberculosis (TB) is still threatening millions of people's lives, especially in developing
countries. One of the major factors contributing to the ongoing epidemic of TB is the lack of a …

Evolution of tuberculosis diagnostics: From molecular strategies to nanodiagnostics

S Mukherjee, S Perveen, A Negi, R Sharma - Tuberculosis, 2023 - Elsevier
Tuberculosis has remained a global concern for public health affecting the lives of people for
ages. Approximately 10 million people are affected by the disease and 1.5 million succumb …