[HTML][HTML] Futibatinib for FGFR2-Rearranged Intrahepatic Cholangiocarcinoma

L Goyal, F Meric-Bernstam… - … England Journal of …, 2023 - Mass Medical Soc
Background Alterations in fibroblast growth factor receptor 2 (FGFR2) have emerged as
promising drug targets for intrahepatic cholangiocarcinoma, a rare cancer with a poor …

Systematic review and meta-analysis of prognostic factors for early recurrence in intrahepatic cholangiocarcinoma after curative-intent resection

WJ Choi, PJ Williams, MPAW Claasen, T Ivanics… - Annals of surgical …, 2022 - Springer
Background Recurrence rates of intrahepatic cholangiocarcinoma (iCCA) after curative
hepatectomy are as high as 50% to 70%, and about half of these recurrences occur within 2 …

Recurrent intrahepatic cholangiocarcinoma–review

Y Bekki, D Von Ahrens, H Takahashi… - Frontiers in …, 2021 - frontiersin.org
Intrahepatic cholangiocarcinoma (ICC) is the second-most common primary liver
malignancy after hepatocellular carcinoma. While surgical resection with negative margin is …

Very early recurrence after liver resection for intrahepatic cholangiocarcinoma: considering alternative treatment approaches

DI Tsilimigras, K Sahara, L Wu, D Moris… - JAMA …, 2020 - jamanetwork.com
Importance Although surgery offers the best chance of a potential cure for patients with
localized, resectable intrahepatic cholangiocarcinoma (ICC), prognosis of patients remains …

3D printing of self-healing personalized liver models for surgical training and preoperative planning

Y Lu, X Chen, F Han, Q Zhao, T Xie, J Wu… - Nature …, 2023 - nature.com
Abstract 3D printing can produce intuitive, precise, and personalized anatomical models,
providing invaluable support for precision medicine, particularly in areas like surgical …

Neoadjuvant chemotherapy for intrahepatic cholangiocarcinoma: a propensity score survival analysis supporting use in patients with high-risk disease

O Utuama, JB Permuth, G Dagne… - Annals of Surgical …, 2021 - Springer
Background Upfront surgery is the current standard for resectable intrahepatic
cholangiocarcinoma (ICC) despite high treatment failure with this approach. We sought to …

Overexpression of TBX3 suppresses tumorigenesis in experimental and human cholangiocarcinoma

S Deng, X Lu, X Wang, B Liang, H Xu, D Yang… - Cell Death & …, 2024 - nature.com
TBX3 behaves as a tumor suppressor or oncoprotein across cancer. However, TBX3
function remains undetermined in intrahepatic cholangiocarcinoma (iCCA), a deadly primary …

The effect of adjuvant therapy for patients with intrahepatic cholangiocarcinoma after surgical resection: A systematic review and meta-analysis

Q Ke, N Lin, M Deng, L Wang, Y Zeng, J Liu - PLoS One, 2020 - journals.plos.org
Backgroud Resection is still the only potentially curative treatment for patients with
intrahepatic cholangiocarcinoma (ICC), but the prognosis remains far from satisfactory …

Development of potent antibody drug conjugates against ICAM1+ cancer cells in preclinical models of cholangiocarcinoma

B Zhu, X Wang, T Shimura, AC Huang, N Kong… - NPJ Precision …, 2023 - nature.com
As a highly lethal adenocarcinoma of the hepatobiliary system, outcomes for
cholangiocarcinoma (CCA) patients remain prominently poor with a 5-year survival of< 10 …

The state of immunotherapy in hepatobiliary cancers

FZ Ilyas, JD Beane, TM Pawlik - Cells, 2021 - mdpi.com
Hepatobiliary cancers, including hepatocellular carcinoma (HCC), cholangiocarcinoma
(CCA), and gallbladder carcinoma (GBC), are lethal cancers with limited therapeutic options …