High‐content video flow cytometry with digital cell filtering for label‐free cell classification by machine learning

C Liu, Z Wang, J Jia, Q Liu, X Su - Cytometry Part A, 2023 - Wiley Online Library
Recent development of imaging flow cytometry (IFC) has enabled the measurements of
single cells with high throughput, where fluorescent labels provide specificity for cellular …

Single-detector dual-modality imaging flow cytometry for label-free cell analysis with machine learning

Z Wang, Q Liu, R Chu, K Song, X Su - Optics and Lasers in Engineering, 2023 - Elsevier
A dual-modality imaging flow cytometer (dIFC) that obtains both brightfield and light
scattering images of single cells simultaneously on one detector was developed. The unique …

Three-dimensional deep regression-based light scattering imaging system for nanoscale exosome analysis

Z Wang, G Chen, S Wang, X Su - Biomedical Optics Express, 2023 - opg.optica.org
Exosomes are extracellular vesicles that serve as promising intrinsic nanoscale biomarkers
for disease diagnosis and treatment. Nanoparticle analysis technology is widely used in the …

Single cell classification of macrophage subtypes by label-free cell signatures and machine learning

D Dannhauser, D Rossi… - Royal Society …, 2022 - royalsocietypublishing.org
Pro-inflammatory (M1) and anti-inflammatory (M2) macrophage phenotypes play a
fundamental role in the immune response. The interplay and consequently the classification …

Multi‐wavelength multi‐direction laser light scattering for cell characterization using machine learning‐based methods

L Liu, MZ Islam, X Liu, M Gupta, W Rozmus… - Cytometry Part …, 2023 - Wiley Online Library
Cell identification and analysis play a crucial role in many biology‐and health‐related
applications. The internal and surface structures of a cell are complex and many of the …

Differentiating single cervical cells by mitochondrial fluorescence imaging and deep learning‐based label‐free light scattering with multi‐modal static cytometry

S Liu, R Chu, J Xie, K Song, X Su - Cytometry Part A, 2023 - Wiley Online Library
Cervical cancer is a high‐risk disease that threatens women's health globally. In this study,
we developed the multi‐modal static cytometry that adopted different features to classify the …

[PDF][PDF] 基于谱分解动态散射成像的细胞无标记检测与分类方法

周雨宁, 夏华, 王晓莉, 柳竞涵, 翟嘉… - 电子测量与仪器 …, 2022 - jemi.cnjournals.com
细胞成像及检测技术在医学研究及临床诊断领域具有重要的研究意义和应用价值,
而无标记与高通量检测尤其具有挑战. 本研究基于动态散射理论的细胞成像方法 …

Identification of refractive index for label-free single cells based on 2D light scattering technology

R Xu, Z Jin, X Wei, X Sun, L Xie - Optics in Health Care and …, 2022 - spiedigitallibrary.org
Two dimensional (2D) light scattering technology is an important part of the single cell
analysis, which can recognize the differences of inherent physical properties of biological …

Image Analysis and Machine Learning for Medical Images

L Liu - 2022 - era.library.ualberta.ca
Medical images play an essential role in detecting and diagnosing numerous diseases. With
different medical imaging modalities, a large volume of images is generated every day …

Machine Learning-assisted Label-Free Cytometry Based on Laser Light Scattering of Single Cells at Multiple Wavelengths and Multiple Directions

X Liu, L Liu, MZ Islam, M Gupta, W Rozmus… - Bio-Optics: Design and …, 2023 - opg.optica.org
Conference title, upper and lower case, bolded, 18 point type, centered Page 1 Machine
Learning-assisted Label-Free Cytometry Based on Laser Light Scattering of Single Cells at …