As a versatile therapeutic modality, peptides attract much attention because of their great
binding affinity, low toxicity, and the capability of targeting traditionally “undruggable” protein …

Covering: up to mid-2009 Prenylated indole alkaloids are hybrid natural products derived
from prenyl diphosphates and tryptophan or its precursors and widely distributed in …

Attachment of isoprene units to various acceptors by prenylation plays an important role in
primary and secondary metabolism of living organisms. Protein prenylation belongs to …

Prenylated aromatic natural products (PANPs) have received much attention due to their
biomedical benefits for human health. The prenylation of aromatic natural products (ANPs) …

Two new diketopiperazine dipeptides, cyclomarazines A and B, were isolated and
characterized along with the new cyclic heptapeptide cyclomarin D from the marine …

Based on the structural information of acetylaszonalenin isolated from Neosartorya fischeri,
a putative biosynthetic gene cluster was identified in the genome sequence of this fungus by …

Aromatic prenyltransferases (PTases), including ABBA-type and dimethylallyl tryptophan
synthase (DMATS)-type enzymes from bacteria and fungi, play important role for …

The ABBA family of aromatic prenyltransferases: broadening natural product diversity - PMC
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Aflatrem is a potent tremorgenic toxin produced by the soil fungus Aspergillus flavus, and a
member of a structurally diverse group of fungal secondary metabolites known as indole …

The linkage of isoprenoid and aromatic moieties, catalyzed by aromatic prenyltransferases
(PTases), leads to an impressive diversity of primary and secondary metabolites, including …