Monoclonal gammopathy of undetermined significance

WI Gonsalves, SV Rajkumar - Annals of internal medicine, 2022 - acpjournals.org
Monoclonal gammopathy of undetermined significance (MGUS) is of considerable clinical
importance to primary care physicians given its high prevalence in the general population …

Prevalence of smoldering multiple myeloma based on nationwide screening

S Thorsteinsdóttir, GK Gíslason, T Aspelund… - Nature medicine, 2023 - nature.com
Smoldering multiple myeloma (SMM) is an asymptomatic precursor to multiple myeloma.
Here we define the epidemiological characteristics of SMM in the general population in …

Defining new reference intervals for serum free light chains in individuals with chronic kidney disease: results of the iStopMM study

TE Long, OS Indridason, R Palsson… - Blood Cancer …, 2022 - nature.com
Serum free light chain (FLC) concentration is greatly affected by kidney function. Using a
large prospective population-based cohort, we aimed to establish a reference interval for …

Advances in MGUS diagnosis, risk stratification, and management: introducing myeloma-defining genomic events

O Landgren - Hematology, 2021 - ashpublications.org
Abstract In the 1960s, Dr Jan Waldenström argued that patients who had monoclonal
proteins without any symptoms or evidence of end-organ damage represented a benign …

Implications and prognostic impact of mass spectrometry in patients with newly-diagnosed multiple myeloma

EK Mai, S Huhn, K Miah, AM Poos, C Scheid… - Blood cancer …, 2023 - nature.com
Mass spectrometry (MS) is a promising tool for monitoring monoclonal protein in plasma cell
dyscrasias. We included 480 transplant-eligible newly-diagnosed multiple myeloma (MM) …

[HTML][HTML] Disease associations with monoclonal gammopathy of undetermined significance can only be evaluated using screened cohorts: results from the population …

AÝ Sigurbergsdóttir, S Rögnvaldsson… - …, 2023 - ncbi.nlm.nih.gov
Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic
precursor condition that precedes multiple myeloma and related disorders but has also been …

Physical and cognitive impact following SARS-CoV-2 infection in a large population-based case-control study

H Holm, EV Ivarsdottir, T Olafsdottir… - Communications …, 2023 - nature.com
Background Persistent symptoms are common after SARS-CoV-2 infection but correlation
with objective measures is unclear. Methods We invited all 3098 adults who tested SARS …

Development of a Multivariable Model to Predict the Need for Bone Marrow Sampling in Persons With Monoclonal Gammopathy of Undetermined Significance: A …

E Eythorsson, S Rognvaldsson… - Annals of Internal …, 2024 - acpjournals.org
Background: Monoclonal gammopathy of undetermined significance (MGUS) and
smoldering multiple myeloma (SMM) are asymptomatic precursor conditions to multiple …

Immunophenotypic assessment of clonal plasma cells and B-cells in bone marrow and blood in the diagnostic classification of early stage monoclonal gammopathies …

O Pérez-Escurza, J Flores-Montero… - Blood Cancer …, 2023 - nature.com
Monoclonal gammopathy of undetermined significance (MGUS) is the earliest discernible
stage of multiple myeloma (MM) and Waldenström's macroglobulinemia (WM). Early …

Autoimmunity, infections, and the risk of monoclonal gammopathy of undetermined significance

AÝ Sigurbergsdóttir, TJ Love… - Frontiers in …, 2022 - frontiersin.org
Various epidemiological studies, including case reports and-series in addition to larger,
population-based studies, have reported an increased prevalence of monoclonal …