Lung cancer is the most common malignancy and leads to around one-quarter of all cancer
deaths. Great advances have been achieved in the treatment of lung cancer with novel …

Fruits and vegetables are used not only for nutritional purposes but also as therapeutics to
treat various diseases and ailments. These food items are prominent sources of …

The drug resistance and low specificity of current available chemotherapeutics to cancer
cells are the main reasons responsible for the failure of cancer chemotherapy and remain …

Background Indole alkaloids are very promising for potential therapeutic purposes and
appear to be particularly effective against respiratory diseases. Several experimental studies …

Naturally occurring indole alkaloids are ubiquitously present in nature and possess
extensive biological properties and structural diversity. Mechanistically, naturally occurring …

An efficient method for the construction of 1, 2, 3-triarylindoles through one-pot
multicomponent reactions using calcium carbide, 3 mol of iodoarenes, and aromatic amines …

The knowledge that natural products (NPs) are potent and selective modulators of important
biomacromolecules (eg, DNA and proteins) has inspired some of the world's most …

The β-carboline skeleton is prevalent in a vast collection of naturally present alkaloids. Most
of these alkaloids and their derivatives have been found to show significant biological …

Cancer is the leading cause of mortality all over the world. Scientific investigation has
demonstrated that disruptions in the process of autophagy are frequently interrelated with …

Seven new deoxyisoaustamide derivatives (1–7) together with known compounds (8–10)
were isolated from the coral-derived fungus Penicillium dimorphosporum KMM 4689. Their …