Older adult participation in cancer clinical trials: a systematic review of barriers and interventions
MS Sedrak, RA Freedman, HJ Cohen… - CA: a cancer journal …, 2021 - Wiley Online Library
Cancer is a disease of aging and, as the world's population ages, the number of older
persons with cancer is increasing and will make up a growing share of the oncology …
persons with cancer is increasing and will make up a growing share of the oncology …
The effect of a geriatric evaluation on treatment decisions for older cancer patients–a systematic review
ME Hamaker, AH Schiphorst… - Acta …, 2014 - Taylor & Francis
Aim. The aim of this systematic review is to summarise all available data on the effect of a
geriatric evaluation on the multidisciplinary treatment of older cancer patients, focussing on …
geriatric evaluation on the multidisciplinary treatment of older cancer patients, focussing on …
Improving the evidence base for treating older adults with cancer: American Society of Clinical Oncology statement
A Hurria, LA Levit, W Dale, SG Mohile… - Journal of Clinical …, 2015 - ascopubs.org
The American Society of Clinical Oncology (ASCO) convened a subcommittee to develop
recommendations on improving the evidence base for treating older adults with cancer in …
recommendations on improving the evidence base for treating older adults with cancer in …
[HTML][HTML] Consideration of comorbidity in treatment decision making in multidisciplinary cancer team meetings: a systematic review
Background Comorbidity is very common among patients with cancer. Multidisciplinary team
meetings (MDTs) are increasingly the context within which cancer treatment decisions are …
meetings (MDTs) are increasingly the context within which cancer treatment decisions are …
Survey of oncologists' perceptions of barriers to accrual of older patients with breast carcinoma to clinical trials
AB Kornblith, M Kemeny, BL Peterson, J Wheeler… - Cancer, 2002 - Wiley Online Library
BACKGROUND Prior research has documented the under‐representation in clinical trials of
older patients with cancer. In part of a larger study to test the magnitude of these barriers to …
older patients with cancer. In part of a larger study to test the magnitude of these barriers to …
[HTML][HTML] ESMO Consensus Conference on malignant lymphoma: general perspectives and recommendations for the clinical management of the elderly patient with …
C Buske, M Hutchings, M Ladetto, V Goede, U Mey… - Annals of …, 2018 - Elsevier
Abstract The European Society for Medical Oncology (ESMO) consensus conference on
mature B cell lymphomas and chronic lymphocytic leukaemia (CLL) was held on 20 June …
mature B cell lymphomas and chronic lymphocytic leukaemia (CLL) was held on 20 June …
Barriers to clinical trial enrollment of older adults with cancer: a qualitative study of the perceptions of community and academic oncologists
MS Sedrak, SG Mohile, V Sun, CL Sun, BT Chen… - Journal of geriatric …, 2020 - Elsevier
Objectives Oncologists can be one of the major barriers to older adult's participation in
research. Multiple studies have described academic clinicians' concerns for not enrolling …
research. Multiple studies have described academic clinicians' concerns for not enrolling …
[HTML][HTML] Rituximab plus bendamustine as front-line treatment in frail elderly (> 70 years) patients with diffuse large B-cell non-Hodgkin lymphoma: a phase II …
S Storti, M Spina, EA Pesce, F Salvi, M Merli… - …, 2018 - ncbi.nlm.nih.gov
We conducted a phase II study to assess activity and safety profile of bendamustine and
rituximab in elderly patients with untreated diffuse large B-cell lymphoma (DLBCL) who were …
rituximab in elderly patients with untreated diffuse large B-cell lymphoma (DLBCL) who were …
Are older adults insufficiently included in clinical trials?—An umbrella review
S Florisson, EK Aagesen, AS Bertelsen… - Basic & Clinical …, 2021 - Wiley Online Library
Abstract Treatment guidelines are primarily based on randomized clinical trials (RCTs).
RCTs tend to some extent to exclude older adults despite the fact that physicians need …
RCTs tend to some extent to exclude older adults despite the fact that physicians need …
Detection of frailty in elderly cancer patients: improvement of the G8 screening test
A Petit-Monéger, M Rainfray, P Soubeyran… - Journal of geriatric …, 2016 - Elsevier
Objective The G8 is a screening test to identify frail elderly patients with cancer. Objectives
were to design and evaluate the performance of alternative tests taking into account other …
were to design and evaluate the performance of alternative tests taking into account other …