Background DNA methylation is an epigenetic chromatin mark that allows heterochromatin
formation and gene silencing. It has a fundamental role in preserving genome stability …

DNA methylation plays a critical role in the regulation of chromatin structure and gene
expression and is involved in a variety of biological processes. The levels and patterns of …

Many chemotherapy regiments are successfully used to treat breast cancer; however, often
breast cancer cells develop drug resistance that usually leads to a relapse and worsening of …

MicroRNAs (miRNAs) are short, noncoding RNA molecules that regulate the expression of a
number of genes involved in cancer; therefore, they offer great diagnostic and therapeutic …

DNA methylation is a heritable and stable epigenetic mark associated with transcriptional
repression. Changes in the patterns and levels of global and regional DNA methylation …

Epigenetics refers to a variety of processes that have heritable effects on gene expression
programs without changes in DNA sequence. Key players in epigenetic control are chemical …

The natural history of cancers associated with virus exposure is intriguing, since only a
minority of human tissues infected with these viruses inevitably progress to cancer …

Autosomal-recessive immunodeficiency, centromeric instability, and facial anomalies (ICF)
syndrome is mainly characterized by recurrent, often fatal, respiratory and gastrointestinal …

Acyl-CoA: glycerol-3-phosphate acyltransferase (GPAT) and acyl-CoA: 1-acyl-glycerol-3-
phosphate acyltransferase (AGPAT) are involved in the de novo synthesis of triacylglycerol …

One of the two X chromosomes in females is epigenetically inactivated, thereby
compensating for the dosage difference in X‐linked genes between XX females and XY …