The roles of extracellular vesicles in the immune system

EI Buzas - Nature Reviews Immunology, 2023 - nature.com
The twenty-first century has witnessed major developments in the field of extracellular
vesicle (EV) research, including significant steps towards defining standard criteria for the …

Isolation and characterization of urinary extracellular vesicles: implications for biomarker discovery

ML Merchant, IM Rood, JKJ Deegens… - Nature Reviews …, 2017 - nature.com
Urine is a valuable diagnostic medium and, with the discovery of urinary extracellular
vesicles, is viewed as a dynamic bioactive fluid. Extracellular vesicles are lipid-enclosed …

Biological properties of extracellular vesicles and their physiological functions

M Yáñez-Mó, PRM Siljander, Z Andreu… - Journal of …, 2015 - Taylor & Francis
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review

AS Azmi, B Bao, FH Sarkar - Cancer and Metastasis Reviews, 2013 - Springer
Trafficking of biological material across membranes is an evolutionary conserved
mechanism and is part of any normal cell homeostasis. Such transport is composed of …

Emerging role of extracellular vesicles in inflammatory diseases

EI Buzas, B György, G Nagy, A Falus… - Nature Reviews …, 2014 - nature.com
The discovery that submicron-sized extracellular vesicles (EVs) are generated by both
prokaryotic and eukaryotic cells might have a profound effect on experimental and clinical …

HUS and atypical HUS

TS Jokiranta - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy characterized by
intravascular hemolysis, thrombocytopenia, and acute kidney failure. HUS is usually …

Extracellular membrane vesicles as a mechanism of cell-to-cell communication: advantages and disadvantages

G Turturici, R Tinnirello, G Sconzo… - American Journal of …, 2014 - journals.physiology.org
Microvesicles represent a newly identified mechanism of intercellular communication. Two
different types of microvesicles have been identified: membrane-derived vesicles (EVs) and …

[HTML][HTML] Small extracellular vesicles in cancer

K Abhange, A Makler, Y Wen, N Ramnauth, W Mao… - Bioactive Materials, 2021 - Elsevier
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …

Proteomics of extracellular vesicles: exosomes and ectosomes

DS Choi, DK Kim, YK Kim… - Mass spectrometry reviews, 2015 - Wiley Online Library
Almost all bacteria, archaea, and eukaryotic cells shed extracellular vesicles either
constitutively or in a regulated manner. These nanosized membrane vesicles are spherical …

Microvesicles: mediators of extracellular communication during cancer progression

V Muralidharan-Chari, JW Clancy… - Journal of cell …, 2010 - journals.biologists.com
Microvesicles are generated by the outward budding and fission of membrane vesicles from
the cell surface. Recent studies suggest that microvesicle shedding is a highly regulated …