Background The global surge in the omicron (B. 1.1. 529) variant has resulted in many
individuals with hybrid immunity (immunity developed through a combination of SARS-CoV …

Background The role of serologic testing for SARS-CoV-2 has evolved during the pandemic
as seroprevalence in global populations has increased. The Infectious Diseases Society of …

This ongoing, open-label, phase 2/3 trial compared the safety and immunogenicity of the
Omicron BA. 4/BA. 5-containing bivalent mRNA-1273.222 vaccine with the ancestral Wuhan …

Wastewater-based surveillance (WBS) has undergone dramatic advancement in the context
of the coronavirus disease 2019 (COVID-19) pandemic. The power and potential of this …

Background China witnessed a surge of Omicron infections after abandoning 'zero
COVID'strategies on 7 December 2022. The authorities report very sparse deaths based on …

Background More than two years into the COVID-19 pandemic, most of the population has
developed anti-SARS-CoV-2 antibodies from infection and/or vaccination. However, public …

Understanding the protection conferred by previous infection against repeat infection,
illness, and severe disease is key to projecting the future epidemiology of COVID-19 and to …

Several teams have been publishing global estimates of excess deaths during the COVID‐
19 pandemic. Here, we examine potential flaws and underappreciated sources of …

SARS-CoV-2 infections manifest with a broad spectrum of presentations, ranging from
asymptomatic infections to severe pneumonia and fatal outcomes. This review centers on …

Limited data is available on the effect of vaccination and previous virus exposure on the
nature of SARS-CoV-2 transmission and immune-pressure on variants. To understand the …