A review on therapeutic potential of Nigella sativa: A miracle herb

A Ahmad, A Husain, M Mujeeb, SA Khan… - Asian Pacific journal of …, 2013 - Elsevier
Abstract Nigella sativa (N. sativa)(Family Ranunculaceae) is a widely used medicinal plant
throughout the world. It is very popular in various traditional systems of medicine like Unani …

Thymoquinone and its therapeutic potentials

S Darakhshan, AB Pour, AH Colagar… - Pharmacological …, 2015 - Elsevier
Herbal medicine has attracted great attention in the recent years and is increasingly used as
alternatives to chemical drugs. Several lines of evidence support the positive impact of …

[HTML][HTML] Therapeutic potential and pharmaceutical development of thymoquinone: a multitargeted molecule of natural origin

SN Goyal, CP Prajapati, PR Gore, CR Patil… - Frontiers in …, 2017 - frontiersin.org
Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-
benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known …

Thymoquinone: potential cure for inflammatory disorders and cancer

CC Woo, AP Kumar, G Sethi, KHB Tan - Biochemical pharmacology, 2012 - Elsevier
Thymoquinone is an active ingredient isolated from Nigella sativa and has been
investigated for its anti-oxidant, anti-inflammatory and anticancer activities in both in vitro …

Thymoquinone: fifty years of success in the battle against cancer models

R Schneider-Stock, IH Fakhoury, AM Zaki… - Drug discovery today, 2014 - Elsevier
Highlights•This year marks 50 years since thymoquinone was isolated from black
seed.•Thymoquinone has had a long history of battling cancer in vitro and in …

Mechanisms of thymoquinone hepatorenal protection in methotrexate‐induced toxicity in rats

AAK El-Sheikh, MA Morsy, AM Abdalla… - Mediators of …, 2015 - Wiley Online Library
To investigate mechanisms by which thymoquinone (TQ) can prevent methotrexate‐(MTX‐)
induced hepatorenal toxicity, TQ (10 mg/kg) was administered orally for 10 days. In …

[HTML][HTML] Thymoquinone defeats diabetes-induced testicular damage in rats targeting antioxidant, inflammatory and aromatase expression

MS Atta, EA Almadaly, AH El-Far, RM Saleh… - International journal of …, 2017 - mdpi.com
Antioxidants have valuable effects on the process of spermatogenesis, particularly with
diabetes mellitus (DM). Therefore, the present study investigated the impact and the …

Black seed thymoquinone improved insulin secretion, hepatic glycogen storage, and oxidative stress in streptozotocin‐induced diabetic male wistar rats

HMA Abdelrazek, OE Kilany… - Oxidative medicine …, 2018 - Wiley Online Library
Diabetes mellitus is one of the metabolic diseases having several complications. Nigella
sativa oil (NSO) might have beneficial effects in the treatment of diabetic complications …

[HTML][HTML] Black seed (Nigella sativa) and its constituent thymoquinone as an antidote or a protective agent against natural or chemical toxicities

A Tavakkoli, A Ahmadi, BM Razavi… - Iranian journal of …, 2017 - ncbi.nlm.nih.gov
Abstract Nigella sativa (N. sativa), which belongs to the botanical family of Ranunculaceae,
is a widely used medicinal plant all over the world. N. sativa seeds and oil have been used …

Therapeutic perspectives of the black cumin component thymoquinone: A review

C Sarkar, S Jamaddar, T Islam, M Mondal, MT Islam… - Food & Function, 2021 - pubs.rsc.org
The dietary phytochemical thymoquinone (TQ), belonging to the family of quinones, mainly
obtained from the black and angular seeds of Nigella sativa, is one of the promising …