Strategies to improve the EPR effect: A mechanistic perspective and clinical translation

M Ikeda-Imafuku, LLW Wang, D Rodrigues… - Journal of Controlled …, 2022 - Elsevier
Many efforts have been made to achieve targeted delivery of anticancer drugs to enhance
their efficacy and to reduce their adverse effects. These efforts include the development of …

Advances in nanomaterial-based targeted drug delivery systems

X Cheng, Q Xie, Y Sun - Frontiers in bioengineering and …, 2023 - frontiersin.org
Nanomaterial-based drug delivery systems (NBDDS) are widely used to improve the safety
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …

Multifunctional AIE nanosphere-based “nanobomb” for trimodal imaging-guided photothermal/photodynamic/pharmacological therapy of drug-resistant bacterial …

B Li, W Wang, L Zhao, D Yan, X Li, Q Gao, J Zheng… - ACS …, 2023 - ACS Publications
Injudicious or inappropriate use of antibiotics has led to the prevalence of drug-resistant
bacteria, posing a huge menace to global health. Here, a self-assembled aggregation …

ε‐poly‐L‐lysine‐modified polydopamine nanoparticles for targeted photothermal therapy of drug‐resistant bacterial keratitis

W Fan, H Han, Z Lu, Y Huang, Y Zhang… - Bioengineering & …, 2023 - Wiley Online Library
Bacterial keratitis can lead to intraocular infection and even blindness without prompt and
potent treatments. Currently, clinical abuse of antibiotics encouraged the evolution of …

Nanoceria for ocular diseases: recent advances and future prospects

W Cui, Y Wang, C Luo, J Xu, K Wang, H Han… - Materials Today Nano, 2022 - Elsevier
Nanoceria, well known as a type of nanozyme, exhibits unique auto-regenerative
antioxidant capacity, mainly originating from a fraction of Ce 3+ ions that can be reversibly …

[HTML][HTML] Nanoparticle formulations for therapeutic delivery, pathogen imaging and theranostic applications in bacterial infections

L Jiang, L Ding, G Liu - Theranostics, 2023 - ncbi.nlm.nih.gov
Pathogenic bacterial infections represent an ever-growing crisis, now significantly
threatening life expectancy across the worldwide population and thus novel approaches to …

99mTc-Labeled, Colistin Encapsulated, Theranostic Liposomes for Pseudomonas aeruginosa Infection

M Karpuz, A Temel, E Ozgenc, Y Tekintas… - AAPS …, 2023 - Springer
Infectious diseases are still the major issue not only due to antibiotic resistance but also
causing deaths if not diagnosed at early-stages. Different approaches including nanosized …

Synergism of 64Cu-Labeled RGD with Anti-PD-L1 Immunotherapy for the Long-Acting Antitumor Effect

X Wen, X Zeng, J Liu, Y Zhang, C Shi, X Wu… - Bioconjugate …, 2022 - ACS Publications
We put forward a novel targeting-triggering-therapy (TTT) scheme that combines 64Cu-
based targeted radionuclide therapy (TRT) with programmed death-ligand 1 (PD-L1)-based …

Quantitative PET tracking of intra-articularly administered 89Zr-peptide-decorated nanoemulsions

S Díez-Villares, L García-Varela… - Journal of Controlled …, 2023 - Elsevier
Intra-articular (IA) administration of drugs for the treatment of diseases such as rheumatoid
arthritis, osteoarthritis and psoriatic arthritis is a common strategy; however, the rapid …

Radiolabeled Liposomes for Nuclear Imaging Probes

HY Low, CT Yang, B Xia, T He, WWC Lam, DCE Ng - Molecules, 2023 - mdpi.com
Quantitative nuclear imaging techniques are in high demand for various disease diagnostics
and cancer theranostics. The non-invasive imaging modality requires radiotracing through …