BACKGROUND Primary ovarian insufficiency (POI) is characterized by marked
heterogeneity, but with a significant genetic contribution. Identifying exact causative genes …

Premature ovarian insufficiency (POI) is one form of female infertility, defined by loss of
ovarian activity before the age of 40 and characterized by amenorrhea (primary or …

Normal levels of reactive oxygen species (ROS) play an important role in regulating follicular
growth, angiogenesis and sex hormone synthesis in ovarian tissue. When the balance …

Primary ovarian insufficiency (POI) is characterized by a loss of ovarian function before the
age of 40 and account for one major cause of female infertility. POI relevance is continuously …

This study was designed to investigate the protective effect of curcumin against d-galactose
(d-gal)-induced premature ovarian failure (POF) in mice. A mouse POF model was induced …

Abstract Peroxiredoxin 4 (Prdx4), a member of the Prdx family, is a vital ER-resident
antioxidant in cells. As revealed in our previous study, Prdx4 expression was detected in …

Premature ovarian failure (POF), a frequently occurring pathology. Chrysin has antioxidant,
anti-inflammatory, anti-apoptotic and other pharmacological activities. This study was …

Classic galactosemia is an inborn error of the metabolism with devastating consequences.
Newborn screening has been successful in markedly reducing the acute neonatal symptoms …

This study aims to investigate the effect as well as mechanism of ginsenoside Rg1 (Rg1) on
premature ovarian failure (POF) induced by d-galactose (d-gal) in mice. C57BL/6 female …

Objective: Neem plant (Azadirachta indica) has been extensively used in Ayurvedic system
of medicine for female fertility regulation for a long time, but its mechanism of action remains …