The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical
research based on biologically accurate screening approaches. Since establishing the 2D in …

Traditional cell lines and xenograft models have been widely recognized and used in
research. As a new research model, organoids have made significant progress and …

The glioma tumor microenvironment (TME), composed of several noncancerous cells and
biomolecules is known for its complexity of cancer-immune system interaction. Given that …

Glioma is the most common primary brain tumor and its prognosis is poor. Despite surgical
removal, glioma is still prone to recurrence because it grows rapidly in the brain, is resistant …

Lacking appropriate model impedes basic and preclinical researches of brain tumors.
Organoids technology applying on brain tumors enables great recapitulation of the original …

Glioblastomas (GBMs) are the brain tumors with the highest malignancy and poorest
prognoses. GBM is characterized by high heterogeneity and resistance to drug treatment …

Glioblastoma multiforme (GBM) is an aggressive brain cancer showing poor prognosis.
Currently, treatment methods of GBM are limited with adverse outcomes and low survival …

Abstract Introduction Glioma stem cells (GSCs) play an important role in glioma recurrence
and chemo‐radiotherapy (CRT) resistance. Currently, there is a lack of efficient treatment …

Glioblastoma (GBM) is one of the most malignant types of brain cancer. Tumor treating fields
(TTFields) is the up-to-date treatment for GBM. However, its molecular mechanism requires …

Neurological disorders are the second cause of death and the leading cause of disability
worldwide. Unfortunately, no cure exists for these disorders, but the actual therapies are only …