[HTML][HTML] Biophysical and molecular mechanisms of ESCRT functions, and their implications for disease

SM Migliano, EM Wenzel, H Stenmark - Current opinion in cell biology, 2022 - Elsevier
The endosomal sorting complex required for transport (ESCRT) machinery evolved early in
evolution to sculpt and cut cellular membranes. Consisting of three subcomplexes termed …

[HTML][HTML] Lessons learned from CHMP2B, implications for frontotemporal dementia and amyotrophic lateral sclerosis

C Ugbode, RJH West - Neurobiology of disease, 2021 - Elsevier
Frontotemporal dementia (FTD) and Amyotrophic Lateral Sclerosis (ALS) are two
neurodegenerative diseases with clinical, genetic and pathological overlap. As such, they …

Insights into the function of ESCRT and its role in enveloped virus infection

C Wang, Y Chen, S Hu, X Liu - Frontiers in Microbiology, 2023 - frontiersin.org
The endosomal sorting complex required for transport (ESCRT) is an essential molecular
machinery in eukaryotic cells that facilitates the invagination of endosomal membranes …

Notch intracellular domain plasmid delivery via Poly (Lactic-Co-Glycolic Acid) nanoparticles to upregulate notch pathway molecules

VL Messerschmidt, U Chintapula… - Frontiers in …, 2021 - frontiersin.org
Notch signaling is a highly conserved signaling system that is required for embryonic
development and regeneration of organs. When the signal is lost, maldevelopment occurs …

Notch Intracellular Domain Plasmid Delivery via Poly (lactic-co-glycolic acid) Nanoparticles to Upregulate Notch Signaling

VL Messerschmidt, AE Kuriakose, U Chintapula… - bioRxiv, 2021 - biorxiv.org
Notch signaling is a highly conserved signaling system that is required for embryonic
development and regeneration of organs. When the signal is lost, maldevelopment occurs …

[图书][B] Poly (Lactic-co-Glycolic Acid) Nanoparticle Delivery of Notch Intracellular Domain Plasmid to Restore Notch Signaling

V Messerschmidt - 2021 - search.proquest.com
Notch signaling is a highly conserved signaling system that is required for embryonic
development and regeneration of organs. When the signal is lost, maldevelopment occurs …