Allogeneic hematopoietic cell transplantation involves consideration of both donor and
recipient characteristics to guide the selection of a suitable graft. Sufficient high-resolution …

Umbilical cord blood is an alternative hematopoietic stem cell source for patients with
hematologic diseases who can be cured by allogeneic hematopoietic cell transplantation …

Background Hematopoietic stem-cell transplantation (HSCT) is a potentially lifesaving
therapy for several blood cancers and other diseases. For patients without a suitable related …

Posttransplant relapse is still the major cause of treatment failure in high-risk acute
leukemia. Attempts to manipulate alloreactive T cells to spare normal cells while killing …

Objectives: Describe the indications for hematopoietic stem cell transplants. Review the
contraindications to hematopoietic stem cell transplants. Outline the potential complications …

Background Umbilical-cord blood has been used as the source of hematopoietic stem cells
in an estimated 30,000 transplants. The limited number of hematopoietic cells in a single …

We studied 459 consecutive patients with hematologic malignancies, median age 44 years
(range, 15 to 71 years), who underwent transplantation with grafts from identical sibling …

BACKGROUND. Delayed hematopoietic recovery is a major drawback of umbilical cord
blood (UCB) transplantation. Transplantation of ex vivo–expanded UCB shortens time to …

We studied the effect of allele-level matching at human leukocyte antigen (HLA)-A,-B,-C, and-
DRB1 in 1568 single umbilical cord blood (UCB) transplantations for hematologic …

Outcomes after unmanipulated haploidentical stem cell transplantation (Haplo) and after
unrelated cord blood transplantation (UCBT) are encouraging and have become alternative …