One of the hallmarks of the parasitic phylum of Apicomplexa is the presence of highly
specialised, apical secretory organelles, called the micronemes and rhoptries that play …

The phylum Apicomplexa has been defined by the presence of the apical complex, a
structure composed of secretory organelles and specific cytoskeletal elements. A …

Apicomplexan parasites use Ca 2+-regulated exocytosis to secrete essential virulence
factors from specialized organelles called micronemes. Ca 2+-dependent protein kinases …

Toxoplasma gondii is an obligate intracellular parasite that causes serious opportunistic
infections, birth defects, and blindness in humans. Microtubules are critically important …

Abstract Ribose-5-phosphate (R5P) is a precursor for nucleic acid biogenesis; however, the
importance and homeostasis of R5P in the intracellular parasite Toxoplasma gondii remain …

To efficiently enter host cells, apicomplexan parasites such as Toxoplasma gondii rely on an
apical complex composed of tubulin‐based structures as well as two sets of secretory …

Toxoplasma, the causative agent of toxoplasmosis in animals and humans, has a
subpellicular cytoskeleton that is involved in motility, cell shape and invasion. Knowledge of …

Phosphatidylinositol (PtdIns) serves as an integral component of eukaryotic membranes;
however, its biosynthesis in apicomplexan parasites remains poorly understood. Here we …

Members of the Apicomplexa phylum possess specialized secretory organelles that
discharge, apically and in a timely regulated manner, key factors implicated in parasite …

Abstract Background The porcine coccidium Cystoisospora suis is characterized by a
complex life-cycle during which asexual multiplication is followed by sexual development …