Improvements in disease management, as well as endoscopic technology and quality, have
dramatically changed the way in which we conceptualize and manage inflammatory bowel …

Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Abstract The 2020 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice
Guideline on the Evaluation and Management of Candidates for Kidney Transplantation is …

Iron deficiency anaemia (IDA) is a major cause of morbidity and burden of disease
worldwide. It can generally be diagnosed by blood testing and remedied by iron …

1.2. Definitions Ulcerative colitis [UC] is a chronic inflammatory condition that causes
continuous mucosal inflammation of the colon, usually without granulomas on biopsy. It …

The strongest nonmodifiable risk factors for CRC and precancerous polyps are age, male
sex, and family history of CRC. Current evidence indicates that smoking, obesity, and diet …

Microsatellite instability (MSI) refers to the hypermutator phenotype secondary to frequent
polymorphism in short repetitive DNA sequences and single nucleotide substitution, as …

In addition to the adenoma to carcinoma sequence, colorectal carcinogenesis can occur via
the serrated pathway. Studies have focused on clarification of categories and molecular …

Background and Aims Patients with inflammatory bowel disease (IBD) have an increased
risk of colorectal cancer (CRC). We performed a systematic review and meta-analysis to …

Heritable factors account for approximately 35% of colorectal cancer (CRC) risk, and almost
30% of the population in the UK have a family history of CRC. The quantification of an …