Cellular immune responses in the pathophysiology of preeclampsia

D Miller, K Motomura, J Galaz… - Journal of Leukocyte …, 2022 - academic.oup.com
Preeclampsia, defined as new-onset hypertension accompanied by proteinuria occurring at
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …

Maternal and congenital toxoplasmosis, currently available and novel therapies in horizon

HS Oz - Frontiers in microbiology, 2014 - frontiersin.org
Over one billion people worldwide are predicted to harbor Toxoplasma infection frequently
with unknown lifelong health consequences. Toxoplasmosis is an important cause of …

B cell development undergoes profound modifications and adaptations during pregnancy in mice

DO Muzzio, R Soldati, J Ehrhardt, K Utpatel… - Biology of …, 2014 - academic.oup.com
Pregnancy hides an immunological riddle combining two antagonistic characteristics of
immunology: the existence of a tolerance that allows the gestation of a semiallogeneic fetus …

The cellular transcriptome in the maternal circulation during normal pregnancy: a longitudinal study

N Gomez-Lopez, R Romero, SS Hassan… - Frontiers in …, 2019 - frontiersin.org
Pregnancy represents a unique immunological state in which the mother adapts to tolerate
the semi-allogenic conceptus; yet, the cellular dynamics in the maternal circulation are …

Human chorionic gonadotropin has anti-inflammatory effects at the maternal-fetal interface and prevents endotoxin-induced preterm birth, but causes dystocia and …

AE Furcron, R Romero, TN Mial, A Balancio… - Biology of …, 2016 - academic.oup.com
Human chorionic gonadotropin (hCG) is implicated in the maintenance of uterine
quiescence by down-regulating myometrial gap junctions during pregnancy, and it was …

B cells: roles in physiology and pathology of pregnancy

JC Liu, Q Zeng, YG Duan, WSB Yeung… - Frontiers in …, 2024 - frontiersin.org
B cells constitute a diverse and adaptable immune cell population with functions that can
vary according to the environment and circumstances. The involvement of B cells in …

Daidzein supplementation improved fecundity in sows via modulation of ovarian oxidative stress and inflammation

K Xie, Y Li, G He, X Zhao, D Chen, B Yu, Y Luo… - The Journal of …, 2022 - Elsevier
Adequate ovarian hormones secretion is essential for pregnancy success. Oxidative
damage and following inflammation can destroy the ovarian normal function in mammals …

Immunologic deviations in recurrent spontaneous abortion mouse model

H Ansariniya, F Zare, N Mosaffa, F Idali… - American Journal of …, 2022 - Wiley Online Library
Background Recurrent spontaneous abortion (RSA) or recurrent pregnancy loss (RPL) is an
abnormality that has a great impact on women's quality of life. RSA is defined as at least …

PD-L2 regulates B-1 cell antibody production against phosphorylcholine through an IL-5–dependent mechanism

JT McKay, MA Haro, CA Daly, RD Yammani… - The Journal of …, 2017 - journals.aai.org
B-1 cells produce natural Abs which provide an integral first line of defense against
pathogens while also performing important homeostatic housekeeping functions. In this …

Are B cells altered in the decidua of women with preterm or term labor?

Y Leng, R Romero, Y Xu, J Galaz… - American Journal of …, 2019 - Wiley Online Library
Problem The immunophenotype of B cells at the maternal‐fetal interface (decidua) in labor
at term and preterm labor is poorly understood. Method of study Decidual tissues were …