Brain–computer interfaces (BCIs) use brain activity to control external devices, thereby
enabling severely disabled patients to interact with the environment. A variety of invasive …

Clinical investigations using stem cell products in regenerative medicine are addressing a
wide spectrum of conditions using a variety of stem cell types. To date, there have been few …

Despite recent developments in innovative treatment strategies, stroke remains one of the
leading causes of death and disability worldwide. Stem cell therapy is currently attracting …

The therapeutic efficacy of stem cells transplanted into an ischaemic brain depends primarily
on the responses of the neurovascular unit. Here, we report the development and …

Background Multipotent adult progenitor cells are a bone marrow-derived, allogeneic, cell
therapy product that modulates the immune system, and represents a promising therapy for …

While preclinical stroke studies have shown that mesenchymal stem cells (MSCs) promote
recovery, few randomized controlled trials (RCT) have assessed cell therapy in humans. In …

Stroke recovery is the next frontier in stroke medicine. While growth in rehabilitation and
recovery research is exponential, a number of barriers hamper our ability to rapidly progress …

Stroke is the third cause of death worldwide and the main cause of chronic, severe adult
disability. We focus on acute ischaemic stroke, which accounts for approximately 80% of all …

Connections between neurons are affected within 3 min of stroke onset by massive ischemic
depolarization and then delayed cell death. Some connections can recover with prompt …

Four decades of preclinical research demonstrating survival, functional integration, and
behavioral effects of transplanted stem cells in experimental stroke models have provided …