Extracellular vesicles and nanoparticles: emerging complexities

DK Jeppesen, Q Zhang, JL Franklin, RJ Coffey - Trends in Cell Biology, 2023 - cell.com
The study of extracellular vesicles (EVs) and nanoparticles (NPs) is rapidly expanding
because recent discoveries have revealed a much greater complexity and diversity than was …

Comprehensive isolation of extracellular vesicles and nanoparticles

Q Zhang, DK Jeppesen, JN Higginbotham… - Nature protocols, 2023 - nature.com
There is an increasing appreciation for the heterogeneous nature of extracellular vesicles
(EVs). In addition, two nonvesicular extracellular nanoparticles (NVEPs), exomeres and …

Exploiting the biogenesis of extracellular vesicles for bioengineering and therapeutic cargo loading

J Rädler, D Gupta, A Zickler, SEL Andaloussi - Molecular Therapy, 2023 - cell.com
Extracellular vesicles (EVs) are gaining increasing attention for diagnostic and therapeutic
applications in various diseases. These natural nanoparticles benefit from favorable safety …

Extracellular vesicles as personalized medicine

DJ Beetler, DN Di Florio, KA Bruno, T Ikezu… - Molecular aspects of …, 2023 - Elsevier
Extracellular vesicles (EVs) are released from all cells in the body, forming an important
intercellular communication network that contributes to health and disease. The contents of …

The biology and function of extracellular vesicles in immune response and immunity

R Kalluri - Immunity, 2024 - cell.com
Extracellular vesicles (EVs), such as ectosomes and exosomes, contain DNA, RNA, proteins
and are encased in a phospholipid bilayer. EVs provide intralumenal cargo for delivery into …

[HTML][HTML] Extracellular vesicles as bioactive nanotherapeutics: an emerging paradigm for regenerative medicine

M Li, F Fang, M Sun, Y Zhang, M Hu, J Zhang - Theranostics, 2022 - ncbi.nlm.nih.gov
In recent decades, extracellular vesicles (EVs), as bioactive cell-secreted nanoparticles
which are involved in various physiological and pathological processes including cell …

L1CAM‐associated extracellular vesicles: A systematic review of nomenclature, sources, separation, and characterization

DE Gomes, KW Witwer - Journal of Extracellular Biology, 2022 - Wiley Online Library
When released into biological fluids like blood or saliva, brain extracellular vesicles (EVs)
might provide a window into otherwise inaccessible tissue, contributing useful biomarkers of …

A beginner's guide to study extracellular vesicles in human blood plasma and serum

R Nieuwland, PRM Siljander - Journal of extracellular vesicles, 2024 - Wiley Online Library
Blood is the most commonly used body fluid for obtaining and studying extracellular vesicles
(EVs). While blood is a standard choice for clinical analysis, using blood as a source of EVs …

[HTML][HTML] Polysaccharide hydrogel platforms as suitable carriers of liposomes and extracellular vesicles for dermal applications

LP Jahromi, M Rothammer, G Fuhrmann - Advanced Drug Delivery …, 2023 - Elsevier
Lipid-based nanocarriers have been extensively investigated for their application in drug
delivery. Particularly, liposomes are now clinically established for treating various diseases …

Extracellular vesicle–based drug delivery in cancer immunotherapy

S Najafi, J Majidpoor, K Mortezaee - Drug Delivery and Translational …, 2023 - Springer
Extracellular vesicles (EVs) are a group of nanoscale membrane-bound organelles
including exosomes, microvesicles (MVs), membrane particles, and apoptotic bodies, which …