The dynamic effects of nicotine on the developing brain
Nicotinic acetylcholine receptors (nAChRs) regulate critical aspects of brain maturation
during the prenatal, early postnatal, and adolescent periods. During these developmental …
during the prenatal, early postnatal, and adolescent periods. During these developmental …
Risk of serious adverse cardiovascular events associated with varenicline: a systematic review and meta-analysis
S Singh, YK Loke, JG Spangler, CD Furberg - Cmaj, 2011 - Can Med Assoc
Background: There have been postmarketing reports of adverse cardiovascular events
associated with the use of varenicline, a widely used smoking cessation drug. We conducted …
associated with the use of varenicline, a widely used smoking cessation drug. We conducted …
Nicotine and brain development
Preclinical studies, using primarily rodent models, have shown acetylcholine to have a
critical role in brain maturation via activation of nicotinic acetylcholine receptors (nAChRs), a …
critical role in brain maturation via activation of nicotinic acetylcholine receptors (nAChRs), a …
the role of the autonomic nervous system in the pathogenesis and therapy of IBD
T Mogilevski, R Burgell, Q Aziz… - Alimentary …, 2019 - Wiley Online Library
Background There is a growing body of evidence implicating a role for the brain‐gut axis in
the pathogenesis of inflammation in patients with IBD. Aims To perform a narrative review of …
the pathogenesis of inflammation in patients with IBD. Aims To perform a narrative review of …
Respiratory sinus arrhythmia: endogenous activation of nicotinic receptors mediates respiratory modulation of brainstem cardioinhibitory parasympathetic neurons
RA Neff, J Wang, S Baxi, C Evans… - Circulation …, 2003 - Am Heart Assoc
The heart rate increases during inspiration and decreases during expiration. This respiratory
sinus arrhythmia (RSA) occurs by modulation of premotor cardioinhibitory parasympathetic …
sinus arrhythmia (RSA) occurs by modulation of premotor cardioinhibitory parasympathetic …
Cholinesterase inhibitors and incidence of bradycardia in patients with dementia in the veterans affairs new England healthcare system
RK Hernandez, W Farwell, MD Cantor… - Journal of the …, 2009 - Wiley Online Library
OBJECTIVES: To quantify the association between cholinesterase inhibitors (ChE‐Is) and a
new diagnosis of bradycardia and to evaluate the clinical significance of bradycardia …
new diagnosis of bradycardia and to evaluate the clinical significance of bradycardia …
The mammalian diving response: inroads to its neural control
WM Panneton, Q Gan - Frontiers in neuroscience, 2020 - frontiersin.org
The mammalian diving response (DR) is a remarkable behavior that was first formally
studied by Laurence Irving and Per Scholander in the late 1930s. The DR is called such …
studied by Laurence Irving and Per Scholander in the late 1930s. The DR is called such …
“Brain–breath” interactions: respiration-timing–dependent impact on functional brain networks and beyond
NH Nakamura, Y Oku, M Fukunaga - Reviews in the Neurosciences, 2024 - degruyter.com
Breathing is a natural daily action that one cannot do without, and it sensitively and intensely
changes under various situations. What if this essential act of breathing can impact our …
changes under various situations. What if this essential act of breathing can impact our …
Respiratory modulation of premotor cardiac vagal neurons in the brainstem
O Dergacheva, KJ Griffioen, RA Neff… - Respiratory physiology & …, 2010 - Elsevier
The respiratory and cardiovascular systems are highly intertwined, both anatomically and
physiologically. Respiratory and cardiovascular neurons are often co-localized in the same …
physiologically. Respiratory and cardiovascular neurons are often co-localized in the same …
Cholinergic neurotransmission in the preBötzinger complex modulates excitability of inspiratory neurons and regulates respiratory rhythm
XM Shao, JL Feldman - Neuroscience, 2005 - Elsevier
We investigated whether there is endogenous acetylcholine (ACh) release in the
preBötzinger Complex (preBötC), a medullary region hypothesized to contain neurons …
preBötzinger Complex (preBötC), a medullary region hypothesized to contain neurons …