Cerebral cavernous malformation: from mechanism to therapy

DA Snellings, CC Hong, AA Ren… - Circulation …, 2021 - Am Heart Assoc
Cerebral cavernous malformations are acquired vascular anomalies that constitute a
common cause of central nervous system hemorrhage and stroke. The past 2 decades have …

Quantitative susceptibility mapping (QSM): decoding MRI data for a tissue magnetic biomarker

Y Wang, T Liu - Magnetic resonance in medicine, 2015 - Wiley Online Library
In MRI, the main magnetic field polarizes the electron cloud of a molecule, generating a
chemical shift for observer protons within the molecule and a magnetic susceptibility …

Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology

S Ayton, Y Wang, I Diouf, JA Schneider… - Molecular …, 2020 - nature.com
Cortical iron has been shown to be elevated in Alzheimer's disease (AD), but the impact of
the directly measured iron on the clinical syndrome has not been assessed. We investigated …

Cerebral microbleeds: imaging and clinical significance

S Haller, MW Vernooij, JPA Kuijer, EM Larsson… - Radiology, 2018 - pubs.rsna.org
Cerebral microbleeds (CMBs), also referred to as microhemorrhages, appear on magnetic
resonance (MR) images as hypointense foci notably at T2*-weighted or susceptibility …

Clinical quantitative susceptibility mapping (QSM): biometal imaging and its emerging roles in patient care

Y Wang, P Spincemaille, Z Liu, A Dimov… - Journal of magnetic …, 2017 - Wiley Online Library
Quantitative susceptibility mapping (QSM) has enabled magnetic resonance imaging (MRI)
of tissue magnetic susceptibility to advance from simple qualitative detection of hypointense …

A method for estimating and removing streaking artifacts in quantitative susceptibility mapping

W Li, N Wang, F Yu, H Han, W Cao, R Romero… - Neuroimage, 2015 - Elsevier
Quantitative susceptibility mapping (QSM) is a novel MRI method for quantifying tissue
magnetic property. In the brain, it reflects the molecular composition and microstructure of …

Toward in vivo histology: a comparison of quantitative susceptibility mapping (QSM) with magnitude-, phase-, and R2⁎-imaging at ultra-high magnetic field strength

A Deistung, A Schäfer, F Schweser, U Biedermann… - Neuroimage, 2013 - Elsevier
Quantitative magnetic susceptibility mapping (QSM) has recently been introduced to provide
a novel quantitative and local MRI contrast. However, the anatomical contrast represented …

Quantitative susceptibility mapping: current status and future directions

EM Haacke, S Liu, S Buch, W Zheng, D Wu… - Magnetic resonance …, 2015 - Elsevier
Quantitative susceptibility mapping (QSM) is a new technique for quantifying magnetic
susceptibility. It has already found various applications in quantifying in vivo iron content …

Background field removal by solving the Laplacian boundary value problem

D Zhou, T Liu, P Spincemaille, Y Wang - NMR in Biomedicine, 2014 - Wiley Online Library
The removal of the background magnetic field is a critical step in generating phase images
and quantitative susceptibility maps, which have recently been receiving increasing …

Quantitative susceptibility mapping: contrast mechanisms and clinical applications

C Liu, H Wei, NJ Gong, M Cronin, R Dibb… - Tomography, 2015 - pmc.ncbi.nlm.nih.gov
Quantitative susceptibility mapping (QSM) is a recently developed magnetic resonance
imaging (MRI) technique for quantifying the spatial distribution of magnetic susceptibility …