4004 ESC Guidelines label use of medication should be limited to situations where it is in
the patient's interest to do so, with regard to the quality, safety, and efficacy of care, and only …

Ventricular arrhythmias are an important cause of morbidity and mortality and come in a
variety of forms, from single premature ventricular complexes to sustained ventricular …

The recommendations listed in this guideline are, whenever possible, evidence based. An
initial extensive evidence review, which included literature derived from research involving …

Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium
not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a …

Cardiac radiotherapy (RT) may be effective in treating heart failure (HF) patients with
refractory ventricular tachycardia (VT). The previously proposed mechanism of radiation …

Failure of drugs and catheter ablation procedures for the treatment of ventricular arrhythmias
is still extremely relevant. Recently, stereotactic body radiotherapy has been introduced to …

Background: Genetic analysis is a first-tier test in dilated cardiomyopathy (DCM). Electrical
phenotypes are common in genetic DCM, but their exact contribution to the clinical course …

Lamins A and C are intermediate filament nuclear envelope proteins encoded by the LMNA
gene. Mutations in LMNA cause autosomal dominant severe heart disease, accounting for …

Patients with cardiac diseases or conditions with high risk of developing cardiac diseases
undergo risk assessment by cardiologists, primary care physicians, and scientists based on …

Cardiomyopathies are a heterogeneous collection of diseases that have in common primary
functional and structural abnormalities of the heart muscle, often genetically determined. The …