Lactic acid bacteria (LAB) are important starter, commensal, or pathogenic microorganisms.
The stress physiology of LAB has been studied in depth for over 2 decades, fueled mostly by …

Protein aggregation occurs as a consequence of perturbations in protein homeostasis that
can be triggered by environmental and cellular stresses. The accumulation of protein …

Here we show that a new class of antibiotics—acyldepsipeptides—has antibacterial activity
against Gram-positive bacteria in vitro and in several rodent models of bacterial infection …

Seasonality, a periodic surge in disease incidence corresponding to seasons or other
calendar periods, characterizes many infectious diseases of public health importance. The …

Summary The Hsp100/Clp ATPases constitute a family of closely related proteins of which
some members function solely as chaperones whereas others additionally can associate …

Background. Changes in serotype prevalence among pneumococcal populations result from
both serotype replacement and serotype (capsular) switching. Temporal changes in …

The seasonality of infectious disease outbreaks suggests that environmental conditions
have a significant effect on disease risk. One of the major environmental factors that can …

Being the principal causative agent of bacterial pneumonia, otitis media, meningitis and
septicemia, the bacterium Streptococcus pneumoniae is a major global health problem. To …

Streptococcus pneumoniae has re-emerged as a major cause of morbidity and mortality
throughout the world and its continuous increase in antimicrobial resistance is rapidly …

Since 1962, when Ferruccio Ritossa discovered new puffing patterns in the polytene
chromosomes of Drosophila incubated at an elevated temperature (153), we have been …